The logic of carotid body connectivity to the brain

T Zera, DJA Moraes, MP da Silva, JP Fisher… - …, 2019 - journals.physiology.org
The carotid body has emerged as a therapeutic target for cardio-respiratory-metabolic
diseases. With the expansive functions of the chemoreflex, we sought mechanisms to …

Neurotransmission and neuromodulation in the chemosensory carotid body

CA Nurse - Autonomic Neuroscience, 2005 - Elsevier
The mammalian carotid body is a small chemosensory organ that helps maintain the
chemical composition of arterial blood via reflex control of ventilation. Thus, in response to …

Carotid body chemoreceptors: physiology, pathology, and implications for health and disease

R Iturriaga, J Alcayaga, MW Chapleau… - Physiological …, 2021 - journals.physiology.org
The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O2
and CO2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to …

Physiology of the carotid body: from molecules to disease

P Ortega-Sáenz, J López-Barneo - Annual review of physiology, 2020 - annualreviews.org
The carotid body (CB) is an arterial chemoreceptor organ located in the carotid bifurcation
and has a well-recognized role in cardiorespiratory regulation. The CB contains …

Synaptic and paracrine mechanisms at carotid body arterial chemoreceptors

CA Nurse - The Journal of physiology, 2014 - Wiley Online Library
Mammalian carotid bodies are the main peripheral arterial chemoreceptors, strategically
located at the bifurcation of the common carotid artery. When stimulated these receptors …

[HTML][HTML] Peripheral chemoreceptors: function and plasticity of the carotid body

P Kumar, NR Prabhakar - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
The discovery of the sensory nature of the carotid body dates back to the beginning of the
20th century. Following these seminal discoveries, research into carotid body mechanisms …

Neurotransmitter and neuromodulatory mechanisms at peripheral arterial chemoreceptors

CA Nurse - Experimental physiology, 2010 - Wiley Online Library
The control of breathing depends critically on sensory inputs to the central pattern generator
of the brainstem, arising from peripheral arterial chemoreceptors located principally in the …

Carotid body chemoreceptors, sympathetic neural activation, and cardiometabolic disease

R Iturriaga, R Del Rio, J Idiaquez, VK Somers - Biological research, 2016 - Springer
The carotid body (CB) is the main peripheral chemoreceptor that senses the arterial PO 2,
PCO 2 and pH. In response to hypoxemia, hypercapnia and acidosis, carotid chemosensory …

Carotid chemoreflex: neural pathways and transmitters

HN Sapru - Frontiers in arterial chemoreception, 1996 - Springer
CAROTID CHEMOREFLEX Page 1 55 CAROTID CHEMOREFLEX Neural Pathways and
Transmitters Hreday N. Sapru Section ofNeurological Surgery and Department of Pharmacology …

Signal processing at mammalian carotid body chemoreceptors

CA Nurse, NA Piskuric - Seminars in cell & developmental biology, 2013 - Elsevier
Mammalian carotid bodies are richly vascularized chemosensory organs that sense blood
levels of O2, CO2/H+, and glucose and maintain homeostatic regulation of these levels via …