The intestinal epithelium forms a key protective barrier that separates internal organs from
the harmful environment of the gut lumen. Increased permeability of the gut barrier is a …

In the intestine, a single layer of epithelial cells effectively separates potentially harmful
luminal content from the underlying tissue. The importance of an intact mucosal layer is …

Epithelia form barriers that are essential to life. This is particularly true in the intestine, where
the epithelial barrier supports nutrient and water transport while preventing microbial …

The intestinal tract is lined by a single layer of columnar epithelial cells that forms a dynamic,
permeable barrier allowing for selective absorption of nutrients, while restricting access to …

Mucosal surfaces are lined by epithelial cells. In the intestine, the epithelium establishes a
selectively permeable barrier that supports nutrient absorption and waste secretion while …

The gastrointestinal tract is a specialized organ in which dynamic interactions between host
cells and the complex environment occur in addition to food digestion. Together with the …

The colonic mucosa provides a vital defensive barrier separating the body from the microbial
populations residing in the intestinal lumen. Indeed, growing evidence shows that loss of …

Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), are complex, multifactorial disorders that lead to chronic and relapsing intestinal …

The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …

The gut mucosa is constantly challenged by a bombardment of foreign antigens and
environmental microorganisms. As such, the precise regulation of the intestinal barrier …