As life expectancy has increased, particularly in developed countries, due to medical
advances and increased prosperity, age-related neurological diseases and mental health …

Growing evidence has shown the beneficial influence of exercise on humans. Apart from
classic cardioprotection, numerous studies have demonstrated that different exercise …

Skeletal muscle is an essential regulator of energy homeostasis and a potent coordinator of
exercise-induced adaptations in other organs including the liver, fat or the brain. Skeletal …

Physical exercise is of great significance for maintaining human health. Exercise can
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …

Neurodegenerative diseases are a group of pathologies that cause severe disability due to
motor and cognitive limitations. In particular, cognitive impairment is a growing health and …

Physical activity may offset cognitive decline and dementia, but the molecular mechanisms
by which it promotes neuroprotection remain elusive. In the absence of disease-modifying …

Human and other animal studies demonstrate that exercise targets many aspects of brain
function and has broad effects on overall brain health. The benefits of exercise have been …

Physical activity—a lifestyle factor that is associated with immune function, neuroprotection,
and energy metabolism—modulates the cellular and molecular processes in the brain that …

Physical exercise is well known as a non-pharmacological and holistic therapy believed to
prevent and mitigate numerous neurological conditions and alleviate ageing-related …

Depression is associated with decreased serotonin metabolism and functioning in the
central nervous system, evidenced by both animal models of depression and clinical patient …