An integrative folate-based metal complex nanotube as a potent antitumor nanomedicine as well as an efficient tumor-targeted drug carrier

LX Liu, BX Li, QY Wang, ZP Dong, HM Li… - Bioconjugate …, 2016 - ACS Publications
Metal–organic complexes (MOCs) are emerging developing functional materials, the
different categories of metal ions and organic biomolecules provide great possibilities for the …

Synthesis, characterization and in vitro anticancer activity of the biomolecule-based coordination complex nanotubes

Y Wang, C Zhang, H Li, G Zhu, SS Bao, S Wei… - Journal of Materials …, 2015 - pubs.rsc.org
Biomolecule-based coordination complex nanoassemblies are a new type of functional
materials that are attracting increasing attention. They could possess functionalities that are …

[HTML][HTML] Lung cancer targeted therapy: folate and transferrin dual targeted, glutathione responsive nanocarriers for the delivery of cisplatin

S Tan, G Wang - Biomedicine & Pharmacotherapy, 2018 - Elsevier
To achieve lung cancer targeted therapy, folic acid (FA) and transferrin (Tf) modified cisplatin
(CDDP) loaded nanoparticles were applied for the in vitro and in vivo evaluation. The aim of …

Recent advances of folate-targeted anticancer therapies and diagnostics: Current status and future prospectives

AM Martínez, M Benito, E Pérez, MD Blanco - Nanostructures for Cancer …, 2017 - Elsevier
Cancer has become one of the main causes of death in developed countries. Nanomedicine
aims to overcome some problems related to this prevalent disease, particularly the lack of …

Folate-targeted single-wall metal-organic nanotubes used as multifunctional drug carriers

L Yang, M Liu, K Huang, X Ai, C Li, J Ma, T Jin… - Applied Surface …, 2017 - Elsevier
Doxorubicin (DOX) is a member of the anthracycline class of chemotherapeutic agents that
are used for the treatment of many common human cancers. A self-assembled …

Quantitative control of active targeting of nanocarriers to tumor cells through optimization of folate ligand density

Z Tang, D Li, H Sun, X Guo, Y Chen, S Zhou - Biomaterials, 2014 - Elsevier
The active targeting delivery system has been widely studied in cancer therapy by utilizing
folate (FA) ligands to generate specific interaction between nanocarriers and folate …

Folate and iron difunctionalized multiwall carbon nanotubes as dual-targeted drug nanocarrier to cancer cells

R Li, R Wu, L Zhao, Z Hu, S Guo, X Pan, H Zou - Carbon, 2011 - Elsevier
A nanomaterial, folate and iron difunctionalized multiwall carbon nanotube (FA-MWCNT@
Fe), has been synthesized by conjugating folate and iron nanoparticles with oxidized multi …

Folate-conjugated nanovehicles: Strategies for cancer therapy

B Farran, RC Montenegro, P Kasa, E Pavitra… - Materials Science and …, 2020 - Elsevier
Cancer theranostics represents a strategy that aims at combining diagnosis with therapy
through the simultaneous imaging and targeted delivery of therapeutics to cancer cells …

Synthesis of 1, 2, 3-triazole linked 5 fluorouracil-carbon dots-folate conjugates for target specific anticancer activity and cell imaging applications

SK Bhattacharyya, D Biswas, N Pandey, S Nandi… - Nano-Structures & Nano …, 2024 - Elsevier
This work provides a unique strategy to anchor the individual properties of fluorophores,
pharmacophores and receptors in a single platform using a copper-catalyzed azide-alkyne …

Expression of folate receptors in nasopharyngeal and laryngeal carcinoma and folate receptor-mediated endocytosis by molecular targeted nanomedicine

M Xie, H Zhang, Y Xu, T Liu, S Chen… - International Journal …, 2013 - Taylor & Francis
Immunohistochemistry and an immunofluorescence technique was used to detect folate
receptor expression in tissue samples and cell lines of head and neck squamous carcinoma …