Pancreatic neuroendocrine tumors (PanNETs) are a rare but clinically important form of
pancreatic neoplasia. To explore the genetic basis of PanNETs, we determined the exomic …

The commonly mutated genes in pancreatic neuroendocrine tumors (PanNETs) are ATRX,
DAXX, and MEN1. We genotyped 64 PanNETs and found 58% carry ATRX, DAXX, and …

Pancreatic neuroendocrine tumors (PanNETs) are complicated and often deadly
neoplasms. A recent increased understanding of their molecular biology has contributed to …

Here we report the DNA methylation profile of 84 sporadic pancreatic neuroendocrine
tumors (PanNETs) with associated clinical and genomic information. We identified three …

The diagnosis of pancreatic neuroendocrine tumours (PanNETs) is increasing owing to
more sensitive detection methods, and this increase is creating challenges for clinical …

The human BON-1 and QGP-1 cell lines are two frequently used models in pancreatic
neuroendocrine tumor (PNET) research. Data on the whole-exome genetic constitution of …

Neuroendocrine tumors (NETs) comprise a group of rare tumors derived from the diffuse
neuroendocrine system or islet endocrine cells of the pancreas. The molecular mechanisms …

Background & Aims Sporadic pancreatic neuroendocrine tumors (pNETs) are rare and
genetically heterogeneous. Chromosome instability (CIN) has been detected in pNETs from …

Well-differentiated pancreatic neuroendocrine tumors (PanNETs) comprise∼ 1–3% of
pancreatic neoplasms. Although long considered as reasonably benign lesions, PanNETs …

Abstract Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NENs) arise throughout
the gut and feature varying biological behaviour and malignant potential. GEP-NENs include …