Tumor promoting role of anti-tumor macrophages in tumor microenvironment

KK Goswami, T Ghosh, S Ghosh, M Sarkar, A Bose… - Cellular …, 2017 - Elsevier
Recent advances in tumor biology demand detailed analysis of the complex interaction of
tumor cells with their adjacent microenvironment (tumor stroma) to understand the various …

New mechanisms of tumor‐associated macrophages on promoting tumor progression: recent research advances and potential targets for tumor immunotherapy

Q Guo, Z Jin, Y Yuan, R Liu, T Xu, H Wei… - Journal of …, 2016 - Wiley Online Library
The majority of basic and clinical studies have shown a protumor function of tumor‐
associated macrophages (TAMs), which represent a large proportion of matrix cells. TAMs …

Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy

Y Komohara, Y Fujiwara, K Ohnishi… - Advanced drug delivery …, 2016 - Elsevier
The macrophage is known to be a multifunctional antigen presenting cells and playing a
central role in inflammation. Macrophages infiltrate into malignant tumor tissues in high …

[HTML][HTML] Tumor-associated macrophages: role in tumorigenesis and immunotherapy implications

S Zhu, Z Luo, X Li, X Han, S Shi, T Zhang - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Tumor-associated macrophages (TAMs) occupy an important position in the tumor
microenvironment (TME), they are a highly plastic heterogeneous population with complex …

The role of macrophages in cancer development and therapy

E Cendrowicz, Z Sas, E Bremer, TP Rygiel - Cancers, 2021 - mdpi.com
Simple Summary Tumor-Associated Macrophages (TAMs) play an important role in the
development of tumors, modulation of neoangiogenesis, immune suppression, and …

Roles of tumor-associated macrophages in tumor progression: implications on therapeutic strategies

S Zhu, M Yi, Y Wu, B Dong, K Wu - Experimental Hematology & Oncology, 2021 - Springer
Macrophages are heterogeneous cells that present as different functional phenotypes due to
their plasticity. They can be classified into two categories, namely M1-and M2-like …

Targeting tumor‑associated macrophages in the tumor microenvironment

K Zhou, T Cheng, J Zhan, X Peng… - Oncology …, 2020 - spandidos-publications.com
Tumor‑associated macrophages (TAMs) are the most abundant population type of tumor‑
infiltrating immune cells found in the tumor microenvironment (TME), and are evolutionarily …

Tumor-associated macrophages: An effective player of the tumor microenvironment

U Basak, T Sarkar, S Mukherjee… - Frontiers in …, 2023 - frontiersin.org
Cancer progression is primarily caused by interactions between transformed cells and the
components of the tumor microenvironment (TME). TAMs (tumor-associated macrophages) …

Tumor-associated macrophages: an accomplice in solid tumor progression

Y Chen, Y Song, W Du, L Gong, H Chang… - Journal of biomedical …, 2019 - Springer
In many solid tumor types, tumor-associated macrophages (TAMs) are important
components of the tumor microenvironment (TME). Moreover, TAMs infiltration is strongly …

Tumor-associated macrophages: a short compendium

H Prenen, M Mazzone - Cellular and Molecular Life Sciences, 2019 - Springer
Macrophages play an important role in tissue development and homeostasis. They serve as
a nexus between adaptive and innate immunity, and employ considerable plasticity. In …