The concept of contrast imaging was introduced to ultrasound almost 30 years ago. The
development of ultrasound contrast agents (USCAs), initially slowed by technical limitations …

During the past 25 years, many attempts have been made to establish effective ultrasound
contrast agents for both cardiac and noncardiac applications. The ideal ultrasound contrast …

Microbubble ultrasound contrast agents (UCAs) were recently approved by the Food and
Drug administration for non-cardiac imaging. The physical principles of UCAs, methods of …

Contrast agents are well established in general radiology. In ultrasonography, however,
there has been a much slower recognition of the advantages of using contrast media. The …

With the introduction of microbubble contrast agents, diagnostic ultrasound has entered a
new era that allows the dynamic detection of tissue flow of both the macro and …

–—For 10 years, it was thought that ultrasound (US) contrast agents could be sufficiently
detected and imaged with the conventional imaging techniques, now referred to as …

The use of contrast-enhanced ultrasound (CEUS) for vascular imaging indications has
increased dramatically during the last decade. Ultrasound contrast agents are gas-filled …

Microbubble contrast agents were introduced more than 25 years ago with the objective of
enhancing blood echoes and enabling diagnostic ultrasound to image the microcirculation …

Microbubble contrast agents for ultrasound (US) have gained increasing interest in recent
years, and contrast-enhanced US (CEUS) is a rapidly evolving field with applications now …

Introduction. Ultrasonography lacked substances to be administered to patients to improve
or increase the diagnositc yield, which is peculiar considering that contrast agents have long …