Cardiovascular disease is the most frequent non-malignant cause of morbidity and mortality
in adult survivors of childhood or adolescent cancer. Thrombin generation (TG) analysis …

Background Thrombin generation, thrombin-antithrombin complex (TAT) levels, and
prothrombin fragment 1+ 2 (F1+ 2) have shown potential as biomarkers of thromboembolic …

The tendency of a plasma sample to generate thrombin, a central enzyme in blood
coagulation, might be an important indicator of prothrombotic risk linked to cardiovascular …

Platelets are suggested to play a crucial role in cancer progression and the prothrombotic
state of cancer patients. Here, we aimed to examine the activation status of platelets in …

Cancer-associated thrombosis (CAT) is a major cause of both morbidity and mortality in
cancer patients. Platelet count has been investigated as a predictor of CAT in various …

Background Thromboembolic disease is a major complication in patients with pancreatic
ductal adenocarcinoma (PDAC). Patients with PDAC often have altered blood cell counts …

Platelet-dependent thrombin generation is a helpful tool to assess ex vivo the interaction
between platelets and plasma coagulation factors in the initiation, amplification, and …

Platelets have a newly appreciated and important role in many cancer-related processes,
including tumor growth and metastases, angiogenesis, and promotion of a hypercoagulable …

Cancer survivors are at an increased risk of thromboembolism compared to the general
pediatric population. Anticoagulant therapy decreases the risk of thromboembolism in …

Background Elevated platelet count is associated with risk of venous thromboembolism in
cancer patients initiating chemotherapy. It is not known whether this risk by platelet count is …