Radiolabeled nanoceria probes may reduce oxidative damages and risk of cancer: A hypothesis for radioisotope-based imaging procedures

MK Bakht, V Hosseini, H Honarpisheh - Medical Hypotheses, 2013 - Elsevier
Low-dose ionizing radiations are commonly utilized in medical centers for diagnostic
imaging procedures. Unfortunately, the absorption of ionizing radiation generates reactive …

[HTML][HTML] Internalized nanoceria modify the radiation-sensitivity profile of MDA MB231 breast carcinoma cells

E Bibb, N Alajlan, S Alsuwailem, B Mitchell, A Brady… - Biology, 2021 - mdpi.com
Simple Summary Cerium oxide nanoparticles (nanoceria) influence its environment by
donating or accepting electrons readily. We investigated nanoceria's ability to modify the …

Selective radioprotection of normal tissues by new cerium oxide nanoparticles

J Colon, S Seal, S Konduri, A Limaye, M Abdelrahim… - Cancer Research, 2007 - AACR
Abstract 754 Background: Selective or preferential protection of normal tissues is an
attractive and potential approach to improve radiotherapy of cancer patients. Currently, we …

[HTML][HTML] Harnessing cerium oxide nanoparticles to protect normal tissue from radiation damage

CH Baker - Translational Cancer Research, 2013 - tcr.amegroups.org
At the onset of radiation exposure, free radicals are formed through ionizing reactions that
are then capable of destroying normal tissues. While cells release a level of protective …

Engineered nanoceria cytoprotection in vivo: mitigation of reactive oxygen species and double-stranded DNA breakage due to radiation exposure

S Das, CJ Neal, J Ortiz, S Seal - Nanoscale, 2018 - pubs.rsc.org
Cerium oxide nanomaterials are known to absorb ionizing radiation energy, as well as to
neutralize free radicals in solution, by undergoing redox changes. We, therefore, proposed …

[HTML][HTML] Reflectance structured illumination imaging of internalized cerium oxide nanoparticles modulating dose-dependent reactive oxygen species in breast cancer …

M Do, K Stinson, R George - Biochemistry and Biophysics Reports, 2020 - Elsevier
Cerium oxide nanoparticles have been shown to sensitize cancer cells to radiation damage.
Their unique redox properties confer excellent therapeutic potential by augmenting radiation …

Radioprotective Potency of Nanoceria

M Alvandi, Z Shaghaghi, S Farzipour… - Current …, 2024 - ingentaconnect.com
Cancer presents a significant medical challenge that requires effective management.
Current cancer treatment options, such as chemotherapy, targeted therapy, radiotherapy …

Quantitative cytotoxicity, cellular uptake and radioprotection effect of cerium oxide nanoparticles in MRC-5 normal cells and MCF-7 cancerous cells

N Abdi Goushbolagh, B Farhood, A Astani, A Nikfarjam… - BioNanoScience, 2018 - Springer
Optimal distribution of cerium oxide nanoparticles (CONPs) or nanoceria can have a
significant impact on their cytotoxicity, cellular uptake, and radioprotection effects. In this …

Protection from radiation-induced pneumonitis using cerium oxide nanoparticles

J Colon, L Herrera, J Smith, S Patil, C Komanski… - … , Biology and Medicine, 2009 - Elsevier
In an effort to combat the harmful effects of radiation exposure, we propose that rare-earth
cerium oxide (CeO2) nanoparticles (free-radical scavengers) protect normal tissue from …

Selective radioprotection of normal tissues with cerium oxide nanoparticles

J Colon, L Herrera, S Patil, S Seal… - International Journal of …, 2008 - redjournal.org
Results Cell viability and cell death assays showed that CeO 2 protected 99% of normal
breast cells from radiation-induced cell death (RICD), whereas breast cancer cells were not …