Radiolabeled nanoceria probes may reduce oxidative damages and risk of cancer: A hypothesis for radioisotope-based imaging procedures
MK Bakht, V Hosseini, H Honarpisheh - Medical Hypotheses, 2013 - Elsevier
Low-dose ionizing radiations are commonly utilized in medical centers for diagnostic
imaging procedures. Unfortunately, the absorption of ionizing radiation generates reactive …
imaging procedures. Unfortunately, the absorption of ionizing radiation generates reactive …
[HTML][HTML] Internalized nanoceria modify the radiation-sensitivity profile of MDA MB231 breast carcinoma cells
E Bibb, N Alajlan, S Alsuwailem, B Mitchell, A Brady… - Biology, 2021 - mdpi.com
Simple Summary Cerium oxide nanoparticles (nanoceria) influence its environment by
donating or accepting electrons readily. We investigated nanoceria's ability to modify the …
donating or accepting electrons readily. We investigated nanoceria's ability to modify the …
Selective radioprotection of normal tissues by new cerium oxide nanoparticles
Abstract 754 Background: Selective or preferential protection of normal tissues is an
attractive and potential approach to improve radiotherapy of cancer patients. Currently, we …
attractive and potential approach to improve radiotherapy of cancer patients. Currently, we …
[HTML][HTML] Harnessing cerium oxide nanoparticles to protect normal tissue from radiation damage
CH Baker - Translational Cancer Research, 2013 - tcr.amegroups.org
At the onset of radiation exposure, free radicals are formed through ionizing reactions that
are then capable of destroying normal tissues. While cells release a level of protective …
are then capable of destroying normal tissues. While cells release a level of protective …
Engineered nanoceria cytoprotection in vivo: mitigation of reactive oxygen species and double-stranded DNA breakage due to radiation exposure
Cerium oxide nanomaterials are known to absorb ionizing radiation energy, as well as to
neutralize free radicals in solution, by undergoing redox changes. We, therefore, proposed …
neutralize free radicals in solution, by undergoing redox changes. We, therefore, proposed …
[HTML][HTML] Reflectance structured illumination imaging of internalized cerium oxide nanoparticles modulating dose-dependent reactive oxygen species in breast cancer …
M Do, K Stinson, R George - Biochemistry and Biophysics Reports, 2020 - Elsevier
Cerium oxide nanoparticles have been shown to sensitize cancer cells to radiation damage.
Their unique redox properties confer excellent therapeutic potential by augmenting radiation …
Their unique redox properties confer excellent therapeutic potential by augmenting radiation …
Radioprotective Potency of Nanoceria
M Alvandi, Z Shaghaghi, S Farzipour… - Current …, 2024 - ingentaconnect.com
Cancer presents a significant medical challenge that requires effective management.
Current cancer treatment options, such as chemotherapy, targeted therapy, radiotherapy …
Current cancer treatment options, such as chemotherapy, targeted therapy, radiotherapy …
Quantitative cytotoxicity, cellular uptake and radioprotection effect of cerium oxide nanoparticles in MRC-5 normal cells and MCF-7 cancerous cells
Optimal distribution of cerium oxide nanoparticles (CONPs) or nanoceria can have a
significant impact on their cytotoxicity, cellular uptake, and radioprotection effects. In this …
significant impact on their cytotoxicity, cellular uptake, and radioprotection effects. In this …
Protection from radiation-induced pneumonitis using cerium oxide nanoparticles
J Colon, L Herrera, J Smith, S Patil, C Komanski… - … , Biology and Medicine, 2009 - Elsevier
In an effort to combat the harmful effects of radiation exposure, we propose that rare-earth
cerium oxide (CeO2) nanoparticles (free-radical scavengers) protect normal tissue from …
cerium oxide (CeO2) nanoparticles (free-radical scavengers) protect normal tissue from …
Selective radioprotection of normal tissues with cerium oxide nanoparticles
Results Cell viability and cell death assays showed that CeO 2 protected 99% of normal
breast cells from radiation-induced cell death (RICD), whereas breast cancer cells were not …
breast cells from radiation-induced cell death (RICD), whereas breast cancer cells were not …