To date, hydrogel-based scaffolds have opened new prospects for potential applications for
drug delivery and regeneration. The novel delivery strategies such as thermo-sensitive …

Spontaneous bone regeneration is heavily restricted because of bone defects, and external
mediation is required to enhance repair and regeneration. Bone tissue engineering (BTE) is …

Chitosan (CS) hydrogels are widely used in wound hemostatic agents due to their superior
biocompatibility, biodegradability, and hemostatic effect. However, most of them fail to …

Thermosensitive chitosan hydrogels have been widely used in drug delivery and tissue
repair, but further applications of these hydrogels have been limited by their weak …

In situ forming injectable hydrogels based on thermosensitive polymers are being
investigated for tissue engineering applications. However, the major limitations of this kind of …

Recently, great attention has been paid to in situ gel-forming chitosan/glycerophosphate
(CS/Gp) formulation due to its high biocompatibility with incorporated cells and medical …

Background: Chitosan thermoresponsive hydrogel is non-covalent crosslinked intelligent
hydrogel. The compositions of the hydrogel determine its gelling property associated with …

A thermosensitive polymer can be held liquid before being injected to deliver living cells or
therapeutic agents and formed monolithic gels when injected in vivo. In this study, chitosan …

Thermogels that undergo temperature-dependent sol-gel transition have recently attracted
attention as a promising biomaterial for injectable tissue engineering. However …

Traditional strategies of bone repair include autografts, allografts and surgical
reconstructions, but they may bring about potential hazard of donor site morbidity, rejection …