A series of novel pyrazolo [1, 5-a] pyrimidine derivatives bearing nitrogen mustard moiety
were designed, synthesized and evaluated for their antiproliferative activities against five …

A novel series of pyrazolo [3, 4-d] pyrimidine derivatives were designed, synthesized and
evaluated for their antiproliferative activity. Among the five compounds selected by NCI …

For anticancer cell line evaluation, a new sequence of pyrazolo [1-5a] pyrimidine and
imidazo [1, 2-b] pyrazole derivatives were synthesized. The reaction of 5-aminopyrazolo with …

Abstract The key precursor E‐3‐(N, N‐dimethylamino)‐1‐(3‐methylthiazolo [3, 2‐a]
benzimidazol‐2‐yl) prop‐2‐en‐1‐one 4 was synthesized in good yield using Gold's reagent …

A novel series of building blocks consisting of benzo [4, 5] thiazolo [1, 2-a] pyrimidine-3-
carboxylate have been synthesized as potential anticancer compounds. These compounds …

A series of pyrazolo [1, 5-a] pyrimidines substituted at C5 with 1-phenylprop-2-en-1-one (6a–
q) and 3-phenylprop-2-en-1-one (7a–k) was synthesized and evaluated for antiproliferative …

A novel series of pyrazolo [1, 5-a] pyrimidine-3-carbonitriles substituted with 7-amino, 7-
substituted amino and 5-substituted amino groups was synthesized. Some of the newly …

A series of pyrazolo [3, 4-d] pyrimidine and urea hybrids have been designed, synthesized
and evaluated for their anticancer activity in vitro and in vivo cancer models. Among them …

A series of N-aryl-7-aryl-pyrazolo [1, 5-a] pyrimidines 18a–u and N-aryl-pyrazolo [1, 5-a]
quinazolines 25a–c were designed and synthesized via the reaction of 5-aminopyrazoles …

Copper–mediated synthesis of various pyrazolo [1, 5–a] pyridine-3-carboxylates has been
described. The biological activities of these molecules have been evaluated against various …