TriTrypDB: a functional genomic resource for the Trypanosomatidae

M Aslett, C Aurrecoechea, M Berriman… - Nucleic acids …, 2010 - academic.oup.com
ABSTRACT TriTrypDB (http://tritrypdb. org) is an integrated database providing access to
genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex …

[HTML][HTML] Genome of the Avirulent Human-Infective Trypanosome—Trypanosoma rangeli

PH Stoco, G Wagner, C Talavera-Lopez… - PLOS Neglected …, 2014 - journals.plos.org
Background Trypanosoma rangeli is a hemoflagellate protozoan parasite infecting humans
and other wild and domestic mammals across Central and South America. It does not cause …

Genome evolution in trypanosomatid parasites

AP Jackson - Parasitology, 2015 - cambridge.org
A decade of genome sequencing has transformed our understanding of how trypanosomatid
parasites have evolved and provided fresh impetus to explaining the origins of parasitism in …

[HTML][HTML] Shining the spotlight on the neglected: new high-quality genome assemblies as a gateway to understanding the evolution of Trypanosomatidae

ATS Albanaz, M Carrington, AO Frolov, AI Ganyukova… - BMC genomics, 2023 - Springer
Background Protists of the family Trypanosomatidae (phylum Euglenozoa) have gained
notoriety as parasites affecting humans, domestic animals, and agricultural plants. However …

[HTML][HTML] Genome of Leptomonas pyrrhocoris: a high-quality reference for monoxenous trypanosomatids and new insights into evolution of Leishmania

P Flegontov, A Butenko, S Firsov, N Kraeva, M Eliáš… - Scientific reports, 2016 - nature.com
Many high-quality genomes are available for dixenous (two hosts) trypanosomatid species
of the genera Trypanosoma, Leishmania, and Phytomonas, but only fragmentary information …

[HTML][HTML] Chromosome level assembly of the hybrid Trypanosoma cruzi genome

DB Weatherly, C Boehlke, RL Tarleton - BMC genomics, 2009 - Springer
Background In contrast to the essentially fully assembled genome sequences of the
kinetoplastid pathogens Leishmania major and Trypanosoma brucei the assembly of the …

[HTML][HTML] The Transcriptome of the Human Pathogen Trypanosoma brucei at Single-Nucleotide Resolution

NG Kolev, JB Franklin, S Carmi, H Shi… - PLoS …, 2010 - journals.plos.org
The genome of Trypanosoma brucei, the causative agent of African trypanosomiasis, was
published five years ago, yet identification of all genes and their transcripts remains to be …

A toolkit enabling efficient, scalable and reproducible gene tagging in trypanosomatids

S Dean, J Sunter, RJ Wheeler, I Hodkinson… - Open …, 2015 - royalsocietypublishing.org
One of the first steps in understanding a protein's function is to determine its localization;
however, the methods for localizing proteins in some systems have not kept pace with the …

[HTML][HTML] Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi

M Parsons, EA Worthey, PN Ward, JC Mottram - BMC genomics, 2005 - Springer
Abstract Background The trypanosomatids Leishmania major, Trypanosoma brucei and
Trypanosoma cruzi cause some of the most debilitating diseases of humankind: cutaneous …

Chromosome-wide analysis of gene function by RNA interference in the African trypanosome

C Subramaniam, P Veazey, S Redmond… - Eukaryotic …, 2006 - Am Soc Microbiol
Trypanosomatids of the order Kinetoplastida are major contributors to global disease and
morbidity, and understanding their basic biology coupled with the development of new drug …