Osteoarthritis is characterized by a chronic, progressive and irreversible degradation of the
articular cartilage associated with joint inflammation and a reparative bone response. More …

Osteoarthritis (OA) is a chronic disease affecting joints and further causing disabilities. This
disease affects around 240 million people worldwide. It is a multifactorial disease, and its …

In vivo articular cartilage degeneration is an essential hallmark of osteoarthritis (OA),
involving chondrocyte senescence, extracellular matrix degradation, chondrocyte death …

Osteoarthritis (OA) is a joint pathology characterized by progressive cartilage degradation.
Medical care is mainly based on alleviating pain symptoms. Compelling studies report the …

Osteoarthritis (OA) is a frequent chronic joint disease in orthopedics that effects individuals
and society significantly. Obesity, aging, genetic susceptibility, and joint misalignment are all …

Osteochondral allograft transplantation is a useful technique to manage larger articular
cartilage injuries. One factor that may compromise the effectiveness of this procedure is …

Chronic inflammation drives the progression of rheumatoid arthritis (RA) and osteoarthritis
(OA) to synovial joint failure. The inflammatory state in both musculoskeletal diseases is …

Chondrocyte apoptosis is known to contribute to articular cartilage damage in osteoarthritis
and is correlated to a number of cartilage disorders. Micromass cultures represent a …

A unique cell type in the cartilage, chondrocyte is responsible for the growth and
maintenance of the tissue through regulating cell proliferation, growth, synthesis and …

Objective The effect of mechanical injury on chondrocyte viability and matrix degradation
was studied. It was proposed that mechanical injury to human cartilage explants results in …