Nanotargeting of drug (s) for delaying dementia: relevance of covid-19 impact on dementia

JS D'Arrigo - American Journal of Alzheimer's Disease & …, 2020 - journals.sagepub.com
By incorporating appropriate drug (s) into lipid (biobased) nanocarriers, one obtains a
combination therapeutic for dementia treatment that targets certain cell-surface scavenger …

[HTML][HTML] Biomaterial to Improve Drug Delivery in Alzheimer's Disease: Linking Major Pathogenic Pathways

JS D'Arrigo - OBM Geriatrics, 2020 - lidsen.com
Abstract Aging, hypertension, diabetes, obesity, atherosclerosis, traumatic brain injury, and
other factors can all synergistically promote diverse pathological mechanisms. These risk …

[HTML][HTML] Drug delivery for neurodegenerative diseases is a problem, but lipid nanocarriers could provide the answer

MR Rafe - Nanotheranostics, 2024 - ncbi.nlm.nih.gov
Neurodegenerative disorders encompass diseases that involve the degeneration of
neurons, particularly those within the central nervous system. These are the most commonly …

[HTML][HTML] Treating dementia early: Limiting cellular damage in brain tissue

JS D'Arrigo - OBM Geriatrics, 2019 - lidsen.com
Much evidence has been published which indicates that microvascular endothelial
dysfunction, due to cerebrovascular risk factors (eg, atherosclerosis, hypertension, obesity …

Biomimetic nanocarrier targeting drug (s) to upstream-receptor mechanisms in dementia: focusing on linking pathogenic cascades

JS D'Arrigo - Biomimetics, 2020 - mdpi.com
Past published studies have already documented that, subsequent to the intravenous
injection of colloidal lipid nanocarriers, apolipoprotein (apo) AI is adsorbed from the blood …

Vascular Risks, Aging, and Late-Onset Dementia: Overlapping Etiologies Point to'Scavenger Receptor'-Mediated Therapeutics

JS D'Arrigo - OBM Geriatrics, 2023 - lidsen.com
Early changes in systemic vascular stiffness and endothelial function can contribute to
altered cerebrovascular hemodynamics and impaired cognitive function; additionally, these …

Lipid nanoparticles in targeting Alzheimer's disease

PN Kendre, A Pote, R Bhalke, BG Prajapati… - Alzheimer's Disease and …, 2024 - Elsevier
Alzheimer's disease (AD) is very common type of disorder like dementia.
Neurodegeneration that is pathophysiologically progressive is a hallmark of the AD. Amyloid …

Targeting Early Dementia: Using Lipid Cubic Phase Nanocarriers to Cross the Blood–Brain Barrier

JS D'Arrigo - Biomimetics, 2018 - mdpi.com
Over the past decades, a frequent co-morbidity of cerebrovascular pathology and
Alzheimer's disease has been observed. Numerous published studies indicate that the …

Dementia and neurodegenerative disorder: An introduction

SV Birajdar, M Mulchandani, F Mazahir… - … -based approaches for the …, 2023 - Elsevier
Neurodegenerative disorders such as “Alzheimer's disease”(AD) are the main preliminary
cause for dementia, which involves around 60–80% of all dementia cases. AD is a …

Treating Alzheimer's disease using nanoparticle-mediated drug delivery strategies/systems

AK Roghani, RI Garcia, A Roghani, A Reddy… - Ageing Research …, 2024 - Elsevier
The administration of promising medications for the treatment of neurodegenerative
disorders (NDDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's …