[HTML][HTML] Role of heat shock proteins in atrial fibrillation: from molecular mechanisms to diagnostic and therapeutic opportunities

D Liu, X Han, Z Zhang, G Tse, Q Shao, T Liu - Cells, 2022 - mdpi.com
Heat shock proteins (HSPs) are endogenous protective proteins and biomarkers of cell
stress response, of which examples are HSP70, HSP60, HSP90, and small HSPs (HSPB) …

[HTML][HTML] The future of atrial fibrillation therapy: intervention on heat shock proteins influencing electropathology is the next in line

EAH Lanters, DMS van Marion, H Steen… - Netherlands Heart …, 2015 - Springer
Atrial fibrillation (AF) is the most common age-related cardiac arrhythmia accounting for one-
third of hospitalisations. Treatment of AF is difficult, which is rooted in the progressive nature …

Heat shock proteins as molecular targets for intervention in atrial fibrillation

BJJM Brundel, L Ke, AJ Dijkhuis, XY Qi… - Cardiovascular …, 2008 - academic.oup.com
Atrial fibrillation (AF) is the most common sustained clinical tachyarrhythmia. AF is a
progressive condition as demonstrated by the finding that maintenance of normal rhythm …

[HTML][HTML] Cardioprotective role of heat shock proteins in atrial fibrillation: from mechanism of action to therapeutic and diagnostic target

SW van Wijk, KS Ramos, BJJM Brundel - International journal of …, 2021 - mdpi.com
Atrial fibrillation (AF) is the most common age-related cardiac arrhythmia worldwide and is
associated with ischemic stroke, heart failure, and substantial morbidity and mortality …

Heat shock protein–inducing compounds as therapeutics to restore Proteostasis in atrial fibrillation

F Hoogstra-Berends, RAM Meijering, D Zhang… - Trends in cardiovascular …, 2012 - Elsevier
Atrial fibrillation (AF) is the most common clinical tachyarrhythmia associated with significant
morbidity and mortality and is expected to affect approximately 30 million North Americans …

Induction of heat shock proteins prevents the arrhythmogenic substrate for atrial fibrillation

N Takahashi, O Wakisaka, H Yoshimatsu… - International Journal of …, 2009 - Taylor & Francis
Atrial fibrillation (AF) is the commonest arrhythmia. Studies have shown that atrial
tachypacing (artificial persistent AF) causes electrical remodelling. This is characterised by …

[HTML][HTML] The protective role of small heat shock proteins in cardiac diseases: key role in atrial fibrillation

X Hu, DMS Van Marion, M Wiersma, D Zhang… - Cell Stress and …, 2017 - Elsevier
Atrial fibrillation (AF) is the most common tachyarrhythmia which is associated with
increased morbidity and mortality. AF usually progresses from a self-terminating paroxysmal …

Heat shock protein upregulation protects against pacing-induced myolysis in HL-1 atrial myocytes and in human atrial fibrillation

BJJM Brundel, RH Henning, L Ke, IC van Gelder… - Journal of molecular and …, 2006 - Elsevier
Atrial fibrillation (AF) causes myocyte stress by inducing structural changes, predominantly
myolysis, which is related to the progression of AF. As heat shock proteins (Hsp) protect …

[HTML][HTML] Loss of proteostatic control as a substrate for atrial fibrillation: a novel target for upstream therapy by heat shock proteins

RAM Meijering, D Zhang, F Hoogstra-Berends… - Frontiers in …, 2012 - frontiersin.org
Atrial fibrillation (AF) is the most common, sustained clinical tachyarrhythmia associated with
significant morbidity and mortality. AF is a persistent condition with progressive structural …

[HTML][HTML] Beat shock proteins and atrial fibrillation

HH Kampinga, RH Henning, IC Van Gelder… - Cell stress & …, 2007 - ncbi.nlm.nih.gov
In this mini-review, the role of heat shock proteins in susceptability to induction of atrial
fibrillation (AF) or in the process of AF is discussed. AF is the most common arrhythmia in …