Core-shell nanoparticles (NPs) with lipid shells and varying water content and rigidity but
with the same chemical composition, size, and surface properties are assembled using a …

The functionalized lipid shell of hybrid nanoparticles plays an important role for improving
their biocompatibility and in vivo stability. Yet few efforts have been made to critically …

The cellular uptake of nanoparticles (NPs) has drawn significant attention due to their great
importance and potential in drug delivery, bioimaging, and specific targeting. Here, we …

Nanoparticles are well established vectors for the delivery of a wide range of biomedically
relevant cargoes. Numerous studies have investigated the impact of size, shape, charge …

Understanding the interactions between nanoparticles (NPs) and lipid bilayers is critical for
the design of drug delivery carriers, biosensors, and biocompatible materials. In particular, it …

Understanding the interaction between functional nanoparticles and cell membranes is
critical to use nanomaterials for broad biomedical applications with minimal cytotoxicity. In …

Internalization of nanoparticles by biomembranes is critical for nanomedicine development;
however, this process, especially its dynamics aspect, is still not well understood. Using …

An enhanced understanding about the interactions between nanomaterials and cell
membranes may have important implications for biomedical applications. In this work …

The cell uptake rate of nanoparticles (NPs) coated with mixed hydrophilic/hydrophobic
ligands is known to be strongly influenced by the ligand pattern on the nanoparticle surface …

Using coarse-grained molecular dynamics simulations, we systematically investigate the
receptor-mediated endocytosis of elastic nanoparticles (NPs) with different sizes, ranging …