The neuropathogenesis of postoperative delirium remains mostly unknown. The gut
microbiota is implicated in the pathogenesis of neurological disorders. We, therefore, set out …

Aims Anesthesia and surgery can cause delirium‐like symptoms postoperatively. Increasing
evidence suggests that gut microbiota is a physiological regulator of the brain. Herein, we …

Aims: Post-operative cognitive dysfunction (POCD) is the decline in cognitive function of the
central nervous system (CNS) after anesthesia/surgery. The present study explored whether …

Postoperative delirium is a common postoperative complication in older patients, and its
pathogenesis and biomarkers remain largely undetermined. The gut microbiota has been …

It is well known that the incidence of postoperative cognitive dysfunction (POCD) is high in
elderly patients. The pathogenesis and therapeutic mechanisms of POCD, however, have …

Background Postoperative cognitive dysfunction (POCD) is associated with increased
morbidity and mortality and has become a major concern for patients and caregivers. POCD …

Perioperative neurocognitive disorder (PND) is a common surgery outcome affecting up to a
third of the elderly patients, and it is associated with high morbidity and increased risk for …

Aging is becoming a severe social phenomenon globally, and the improvements in health
care and increased health awareness among the elderly have led to a dramatic increase in …

With the aging of the world population, and improvements in medical and health
technologies, there are increasing numbers of elderly patients undergoing anaesthesia and …

Background Surgery-induced neuroinflammation plays an important role in postoperative
cognitive dysfunction (POCD). Gut microbiota is a key regulator of neurological …