Silencing of SNHG12 enhanced the effectiveness of MSCs in alleviating ischemia/reperfusion injuries via the PI3K/AKT/mTOR signaling pathway

Y Li, S Guo, W Liu, T Jin, X Li, X He, X Zhang… - Frontiers in …, 2019 - frontiersin.org
Previous studies have reported that the long non-coding RNA SNHG12 (lncRNA SNHG12)
plays a critical role in regulating the function of mesenchymal stem cells (MSCs); however …

Overexpression of long non-coding RNA SNHG16 against cerebral ischemia-reperfusion injury through miR-106b-5p/LIMK1 axis

H Pan, F Zhao, Y Yang, N Chang - Life Sciences, 2020 - Elsevier
Long non-coding RNA (LncRNA) involved in types of physiological insults and diseases via
regulating the responses of complex molecular, including cerebral ischemia-reperfusion …

[HTML][HTML] Inhibition of long noncoding RNA SNHG15 ameliorates hypoxia/ischemia-induced neuronal damage by regulating miR-302a-3p/STAT1/NF-κB axis

C Hu, C Li, Q Ma, R Wang, Y He, H Wang… - Yonsei Medical …, 2021 - ncbi.nlm.nih.gov
Purpose Ischemic brain injury results in high mortality and serious neurologic morbidity.
Here, we explored the role of SNHG15 in modulating neuronal damage and microglial …

LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway

WL Yin, WG Yin, BS Huang, LX Wu - Neuroscience letters, 2019 - Elsevier
Cerebral ischemia caused severe disability, and associated with a series of neurological
events. Long non-coding RNA SNHG12 was found to be upregulated in mouse brain …

Mechanism of lncRNA SNHG16 in oxidative stress and inflammation in oxygen-glucose deprivation and reoxygenation-induced SK-N-SH cells

X Cao, J Ma, S Li - Bioengineered, 2022 - Taylor & Francis
Cerebral ischemia-reperfusion injury imposes a clinical challenge for physicians in the wake
of ischemic stroke. Meanwhile, recent evidence has come to light eliciting the …

LncRNA SNHG12 ameliorates brain microvascular endothelial cell injury by targeting miR-199a

FQ Long, QJ Su, JX Zhou, DS Wang, PX Li… - Neural regeneration …, 2018 - journals.lww.com
Long non-coding RNAs regulate brain microvascular endothelial cell death, the
inflammatory response and angiogenesis during and after ischemia/reperfusion and oxygen …

Long non-coding RNA SNHG14 promotes microglia activation by regulating miR-145-5p/PLA2G4A in cerebral infarction

X Qi, M Shao, H Sun, Y Shen, D Meng, W Huo - Neuroscience, 2017 - Elsevier
Activated microglia cells (MCs) are able to release a large amount of inflammatory cytokines
after ischemic stroke, which exacerbates neuron damage. In this study, we explored the …

Downregulation of lncRNA SNHG14 alleviates neurons injury by modulating the miR-181c-5p/BMF axis in ischemic stroke

X Bu, Y Zhao, M Chang, X Ge - Brain Research Bulletin, 2021 - Elsevier
Purpose Our study aims to explore the role and mechanism of lncRNA small nucleolar RNA
host gene 14 (SNHG14) in brain injury caused by ischemic stroke (IS). Methods Middle …

LncRNA SNHG4 attenuates inflammatory responses by sponging miR-449c-5p and up-regulating STAT6 in microglial during cerebral ischemia-reperfusion injury

S Zhang, W Sun, Z Liang, X Yin, Z Ji… - Drug design …, 2020 - Taylor & Francis
Background Inflammatory response mediated by microglia plays a key role in cerebral
ischemia-reperfusion injury. This study intends to probe the role of lncRNA SNHG4 in …

LncRNA Snhg8 attenuates microglial inflammation response and blood–brain barrier damage in ischemic stroke through regulating miR‐425‐5p mediated SIRT1/NF …

J Tian, Y Liu, Z Wang, S Zhang, Y Yang… - … of Biochemical and …, 2021 - Wiley Online Library
Increasing studies have indicated that abnormal expressed long noncoding RNAs
(lncRNAs) play a vital role in ischemic stroke. Small nucleolar RNA host gene 8 (Snhg8), a …