Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance

K Natarajan, Y Xie, MR Baer, DD Ross - Biochemical pharmacology, 2012 - Elsevier
Since cloning of the ATP-binding cassette (ABC) family member breast cancer resistance
protein (BCRP/ABCG2) and its characterization as a multidrug resistance efflux transporter …

Structure and function of the human breast cancer resistance protein (BCRP/ABCG2)

Z Ni, Z Bikadi, MF Rosenberg… - Current drug metabolism, 2010 - ingentaconnect.com
The human breast cancer resistance protein (BCRP/ABCG2) is the second member of the G
subfamily of the large ATPbinding cassette (ABC) transporter superfamily. BCRP was …

Breast cancer resistance protein (BCRP/ABCG2)

F Staud, P Pavek - The international journal of biochemistry & cell biology, 2005 - Elsevier
Breast cancer resistance protein (BCRP) was identified 7 years ago as the most recent
member of ABC drug efflux membrane transporters. It is a 655 amino acid peptide with an …

Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport—an update

Q Mao, JD Unadkat - The AAPS journal, 2015 - Springer
The human breast cancer resistance protein (BCRP, gene symbol ABCG2) is an ATP-
binding cassette (ABC) efflux transporter. It was so named because it was initially cloned …

[HTML][HTML] Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression

T Nakanishi, DD Ross - Chinese journal of cancer, 2012 - ncbi.nlm.nih.gov
Breast cancer resistance protein (BCRP)/ATP-binding cassette subfamily G member 2
(ABCG2) is an ATP-binding cassette (ABC) transporter identified as a molecular cause of …

Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy

K Noguchi, K Katayama, J Mitsuhashi… - Advanced drug delivery …, 2009 - Elsevier
The breast cancer resistance protein, BCRP/ABCG2, is a half-molecule ATP-binding
cassette transporter that facilitates the efflux of various anticancer agents from the cell …

The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins

AE van Herwaarden, AH Schinkel - Trends in pharmacological sciences, 2006 - cell.com
The breast cancer resistance protein [BCRP (also known as ABCG2)] belongs to the ATP
binding cassette (ABC) family of transmembrane drug transporters. BCRP has a broad …

Role of the breast cancer resistance protein (ABCG2) in drug transport

Q Mao - The AAPS journal, 2005 - Springer
The 72-kDa breast cancer resistance protein (BCRP) is the second member of the subfamily
G of the human ATP binding cassette (ABC) transporter superfamily and thus also …

Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

L Austin Doyle, DD Ross - Oncogene, 2003 - nature.com
Observations of functional adenosine triphosphate (ATP)-dependent drug efflux in certain
multidrug-resistant cancer cell lines without overexpression of P-glycoprotein or multidrug …

Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2)

T Janvilisri, S Shahi, H Venter… - Biochemical …, 2005 - portlandpress.com
The human BCRP (breast cancer resistance protein, also known as ABCG2) is an ABC (ATP-
binding cassette) transporter that extrudes various anticancer drugs from cells, causing …