Circadian rhythms and cardiovascular health

F Portaluppi, R Tiseo, MH Smolensky, RC Hermida… - Sleep medicine …, 2012 - Elsevier
The functional organization of the cardiovascular system shows clear circadian rhythmicity.
These and other circadian rhythms at all levels of organization are orchestrated by a central …

[HTML][HTML] Role of the circadian system in cardiovascular disease

SS Thosar, MP Butler, SA Shea - The Journal of clinical …, 2018 - Am Soc Clin Investig
All species organize behaviors to optimally match daily changes in the environment, leading
to pronounced activity/rest cycles that track the light/dark cycle. Endogenous, approximately …

[HTML][HTML] Circadian clock and the onset of cardiovascular events

N Takeda, K Maemura - Hypertension Research, 2016 - nature.com
The onset of cardiovascular diseases often shows time-of-day variation. Acute myocardial
infarction or ventricular arrhythmia such as ventricular tachycardia occurs mainly in the early …

Chronopharmacology and chronotherapy of cardiovascular medications: relevance to prevention and treatment of coronary heart disease

MH Smolensky, F Portaluppi - American Heart Journal, 1999 - Elsevier
Biological functions and processes, including cardiovascular ones, exhibit significant
circadian (24-hour) and other period rhythms. Ambulatory blood pressure assessment …

Diurnal and twenty-four hour patterning of human diseases: cardiac, vascular, and respiratory diseases, conditions, and syndromes

MH Smolensky, F Portaluppi, R Manfredini… - Sleep Medicine …, 2015 - Elsevier
Various medical conditions, disorders, and syndromes exhibit predictable-in-time diurnal
and 24 h patterning in the signs, symptoms, and grave nonfatal and fatal events, eg …

Circadian rhythm in the cardiovascular system: chronocardiology

YF Guo, PK Stein - American heart journal, 2003 - Elsevier
BACKGROUND: We reviewed recent progress in the study of the chronobiological aspects
of the cardiovascular system. METHODS: Medline was used as the main search tool, and …

Consequences of circadian and sleep disturbances for the cardiovascular system

FJ Alibhai, EV Tsimakouridze, CJ Reitz, WG Pyle… - Canadian Journal of …, 2015 - Elsevier
Circadian rhythms play a crucial role in our cardiovascular system. Importantly, there has
been a recent flurry of clinical and experimental studies revealing the profound adverse …

[HTML][HTML] Therapeutic applications of circadian rhythms for the cardiovascular system

EV Tsimakouridze, FJ Alibhai, TA Martino - Frontiers in pharmacology, 2015 - frontiersin.org
The cardiovascular system exhibits dramatic time-of-day dependent rhythms, for example
the diurnal variation of heart rate, blood pressure, and timing of onset of adverse …

[HTML][HTML] Circadian clock and cardiovascular disease

N Takeda, K Maemura - Journal of cardiology, 2011 - Elsevier
Both the physiological and pathological functions of cardiovascular organs are closely
related to circadian rhythm, an endogenously driven 24-h cycle. Heart rate, blood pressure …

[HTML][HTML] Circadian rhythm of cardiac electrophysiology, arrhythmogenesis, and the underlying mechanisms

N Black, A D'Souza, Y Wang, H Piggins, H Dobrzynski… - Heart rhythm, 2019 - Elsevier
Cardiac arrhythmias are a leading cause of cardiovascular death. It has long been accepted
that life-threatening cardiac arrhythmias (ventricular tachycardia, ventricular fibrillation, and …