Despite recent remarkable advances in microscopic techniques, it still remains very
challenging to directly observe the complex structure of cytoplasmic organelles in live cells …

Bright-field light microscopy and related phase-sensitive techniques play an important role
in life sciences because they provide facile and label-free insights into biological specimens …

Interferometric scattering microscopy (iSCAT) is a light scattering-based imaging modality
that offers a unique combination of imaging speed and precision for tracking nanoscopic …

Optical interference microscopy is a powerful bioimaging technique by measuring the
complex light fields associated with the specimen. Nowadays, the state-of-the-art …

Interferometric scattering microscopy (iSCAT) is an extremely sensitive imaging method
based on the efficient detection of light scattered by nanoscopic objects. The ability to, at …

Interferometric scattering (iSCAT) microscopy is a highly sensitive imaging technique that
uses common-path interferometry to detect the linear scattering fields associated with …

There are several methods for visualizing purified biomolecules near surfaces. Total-internal
reflection fluorescence (TIRF) microscopy is a commonly used method, but has the …

Emerging questions in cell biology necessitate nanoscale imaging in live cells. Here we
present scanning angle interference microscopy, which is capable of localizing fluorescent …

Live-cell imaging is a powerful technique to study the dynamics and mechanics of various
biological molecules like proteins, organelles, DNA, and RNA. With the rapid evolution of …

We demonstrate far-field fluorescence microscopy with a focal-plane resolution of 15–20 nm
in biological samples. The 10-to 12-fold multilateral increase in resolution below the …