Polymeric micelles have been widely explored preclinically as suitable delivery systems for
poorly soluble chemotherapeutic drugs in cancer therapy. The present study reported the …

Purpose This work describes the synthesis of block co-polymeric micelles, methoxy-poly
(ethylene glycol)-poly (D, L-lactide)(mPEG-PLA) to encapsulate Curcumin (CUR), thereby …

Abstract Poly (lactide-co-glycolide)-cholesterol (PLGA-C)-based nanoparticles (NPs) were
developed for the tumor-targeted delivery of curcumin (CUR). PLGA-C/CUR NPs with∼ 200 …

Targeting delivery system use natural drugs for tumor cells is an appealing platform help to
reduce the side effects and enhance the therapeutic effects of the drug. In this study, we …

Modifying positive surface charge and reducing bulk size of nanoparticles has been proven
beneficial to cancer cellular delivery, but meanwhile results in fast clearance and unspecific …

In recent years, actively targeted drug delivery systems have been utilized in pre-clinical
studies for site-specific delivery of drugs, which reduces toxicities associated with …

Among the potent anticancer agents, curcumin is known as an effective agent against many
different types of cancer cells. Its clinical applications have been limited because of …

For efficient therapy, optimized polymer micelle drug delivery systems require stability during
circulation, appropriate diameters for targeting, and controlled drug release at the lesion site …

Purpose Polymeric micelles are attractive nanocarriers for tumor-targeted delivery of
paclitaxel (PTX). High antitumor efficacy and low toxicity require that PTX mainly …

Cancer, a cause of high mortality in the world today, is a serious threat to the public health
security of various countries. Targeted drug delivery systems with good biocompatibility …