Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast
Cryptic transcription is widespread and generates a heterogeneous group of RNA
molecules of unknown function. To improve our understanding of cryptic transcription, we …
molecules of unknown function. To improve our understanding of cryptic transcription, we …
[HTML][HTML] Chromatin-and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome
Previous studies in Saccharomyces cerevisiae have demonstrated that cryptic promoters
within coding regions activate transcription in particular mutants. We have performed a …
within coding regions activate transcription in particular mutants. We have performed a …
Bidirectional terminators in Saccharomyces cerevisiae prevent cryptic transcription from invading neighboring genes
N Uwimana, P Collin, C Jeronimo… - Nucleic acids …, 2017 - academic.oup.com
Transcription can be quite disruptive for chromatin so cells have evolved mechanisms to
preserve chromatin integrity during transcription, thereby preventing the emergence of …
preserve chromatin integrity during transcription, thereby preventing the emergence of …
Molecular dissection of the genetic mechanisms that underlie expression conservation in orthologous yeast ribosomal promoters
Recent studies have shown a surprising phenomenon, whereby orthologous regulatory
regions from different species drive similar expression levels despite being highly diverged …
regions from different species drive similar expression levels despite being highly diverged …
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes
K Kimura, A Wakamatsu, Y Suzuki, T Ota… - Genome …, 2006 - genome.cshlp.org
By analyzing 1,780,295 5′-end sequences of human full-length cDNAs derived from 164
kinds of oligo-cap cDNA libraries, we identified 269,774 independent positions of …
kinds of oligo-cap cDNA libraries, we identified 269,774 independent positions of …
Noncanonical transcript forms in yeast and their regulation during environmental stress
OK Yoon, RB Brem - Rna, 2010 - rnajournal.cshlp.org
Surveys of transcription in many organisms have observed widespread expression of RNAs
with no known function, encoded within and between canonical coding genes. The search to …
with no known function, encoded within and between canonical coding genes. The search to …
Genomic analysis of a synthetic reversed sequence reveals default chromatin states in yeast and mammalian cells
Up to 93% of the human genome may show evidence of transcription, yet annotated
transcripts account for less than 5%. It is unclear what makes up this major discrepancy, and …
transcripts account for less than 5%. It is unclear what makes up this major discrepancy, and …
Pervasive and dynamic transcription initiation in Saccharomyces cerevisiae
Transcription initiation is finely regulated to ensure proper expression and function of genes.
The regulated transcription initiation in response to various environmental stimuli in a classic …
The regulated transcription initiation in response to various environmental stimuli in a classic …
[HTML][HTML] Repression of divergent noncoding transcription by a sequence-specific transcription factor
Many active eukaryotic gene promoters exhibit divergent noncoding transcription, but the
mechanisms restricting expression of these transcripts are not well understood. Here, we …
mechanisms restricting expression of these transcripts are not well understood. Here, we …
Widespread bidirectional promoters are the major source of cryptic transcripts in yeast
Pervasive and hidden transcription is widespread in eukaryotes,,,, but its global level, the
mechanisms from which it originates and its functional significance are unclear. Cryptic …
mechanisms from which it originates and its functional significance are unclear. Cryptic …