Big Potassium (BK) ion channels in biology, disease and possible targets for cancer immunotherapy
L Ge, NT Hoa, Z Wilson, G Arismendi-Morillo… - International …, 2014 - Elsevier
Abstract The Big Potassium (BK) ion channel is commonly known by a variety of names
(Maxi-K, KCNMA1, slo, stretch-activated potassium channel, KCa1. 1). Each name reflects a …
(Maxi-K, KCNMA1, slo, stretch-activated potassium channel, KCa1. 1). Each name reflects a …
Potassium channels: novel emerging biomarkers and targets for therapy in cancer
M D'Amico, L Gasparoli… - Recent patents on anti …, 2013 - ingentaconnect.com
K+ Channels form the largest family among ion channels. Besides regulating many
physiological functions, K+ channels, being aberrantly expressed in different types of …
physiological functions, K+ channels, being aberrantly expressed in different types of …
[HTML][HTML] Potassium channels as a target for cancer therapy: Current perspectives
Potassium (K+) channels are highly regulated membrane proteins that control the potassium
ion flux and respond to different cellular stimuli. These ion channels are grouped into three …
ion flux and respond to different cellular stimuli. These ion channels are grouped into three …
[HTML][HTML] SKCa-and Kv1-type potassium channels and cancer: Promising therapeutic targets?
M Dupuy, M Gueguinou, M Potier-Cartereau… - Biochemical …, 2023 - Elsevier
Ion channels are transmembrane structures that allow the passage of ions across cell
membranes such as the plasma membrane or the membranes of various organelles like the …
membranes such as the plasma membrane or the membranes of various organelles like the …
Roles of K+ channels in regulating tumour cell proliferation and apoptosis
Z Wang - Pflügers Archiv, 2004 - Springer
K+ channels are a most diverse class of ion channels in the cytoplasmic membrane and are
distributed widely in a variety of cells including cancer cells. Cell proliferation and apoptosis …
distributed widely in a variety of cells including cancer cells. Cell proliferation and apoptosis …
NS-11021 modulates cancer-associated processes independently of BK channels in melanoma and pancreatic duct adenocarcinoma cell lines
A Remigante, P Zuccolini, R Barbieri, L Ferrera… - Cancers, 2021 - mdpi.com
Simple Summary Potassium channels permit the selective passage of K+ ions across the
cell me brane and are important for setting the membrane potential and for the transmission …
cell me brane and are important for setting the membrane potential and for the transmission …
[HTML][HTML] Glioma big potassium channel expression in human cancers and possible T cell epitopes for their immunotherapy
L Ge, NT Hoa, AN Cornforth, DA Bota, A Mai… - The Journal of …, 2012 - journals.aai.org
Big potassium (BK) ion channels have several spliced variants. One spliced variant initially
described within human glioma cells is the glioma BK (gBK) channel. This isoform consists …
described within human glioma cells is the glioma BK (gBK) channel. This isoform consists …
Potassium channels: Novel targets for tumor diagnosis and chemoresistance
M Li, P Tian, Q Zhao, X Ma, Y Zhang - Frontiers in Oncology, 2023 - frontiersin.org
In recent years, the role of potassium channels in tumors has been intensively studied.
Potassium channel proteins are widely involved in various physiological and pathological …
Potassium channel proteins are widely involved in various physiological and pathological …
BKCa channels as physiological regulators: a focused review
F Vetri, M Saha Roy Choudhury… - Journal of Receptor …, 2014 - Taylor & Francis
Large-conductance Ca2+-and voltage-gated big K+ (BKCa, MaxiK, or Slo1) channels are
expressed in almost every cell of mammalian tissues and participate in a multitude of …
expressed in almost every cell of mammalian tissues and participate in a multitude of …
The roles of K+ channels in cancer
LA Pardo, W Stühmer - Nature Reviews Cancer, 2014 - nature.com
Potassium channels are transmembrane proteins that selectively facilitate the flow of
potassium ions down an electrochemical gradient. These molecules have been studied in …
potassium ions down an electrochemical gradient. These molecules have been studied in …
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