Electronic coupling in 1, 2, 3-triazole bridged ferrocenes and its impact on reactive oxygen species generation and deleterious activity in cancer cells

P Biegański, E Kovalski, N Israel, E Dmitrieva… - Inorganic …, 2022 - ACS Publications
Mixed-valence (MV) binuclear ferrocenyl compounds have long been studied as models for
testing theories of electron transfer and in attempts to design molecular-scale electronic …

Anticancer effect of an electronically coupled oligoferrocene

G Zeh, P Haines, ME Miehlich, T Kienz… - …, 2020 - ACS Publications
The mode of anticancer activity of simple ferrocenes often relies on their intracellular
oxidation with the formation of cytotoxic ferrocenium species. The former compounds should …

[HTML][HTML] Ferrocene-triazole conjugates: do we know why they are biologically active?

M Koszytkowska-Stawińska, W Buchowicz - Dalton Transactions, 2023 - pubs.rsc.org
The bioorganometallic chemistry of ferrocene has been gaining significance in recent years.
This review presents ferrocene-triazole conjugates displaying significant biological …

Synthesis of redox-active ferrocene pyrazole conjugates and their cytotoxicity in human mammary adenocarcinoma MCF-7 cells

WCM Duivenvoorden, Y Liu, G Schatte… - Inorganica chimica acta, 2005 - Elsevier
The redox-active ferrocenoyl modified pyrazole ligand (3-Fc-AMP) readily coordinates to a
variety of transition metal ions. Here, we describe our findings regarding the synthesis and …

The synthesis, structure, electrochemistry and in vitro anticancer activity studies of ferrocenyl-thymine conjugates

K Kowalski, A Koceva-Chyła, A Pieniążek… - Journal of …, 2012 - Elsevier
We report the synthesis of two ferrocenyl-thymine conjugates; acyclonucleoside 11d and its
precursor 11c. The key step of our synthetic approach relied on a Michael addition reaction …

Ferrocenes as potential chemotherapeutic drugs: Synthesis, cytotoxic activity, reactive oxygen species production and micronucleus assay

WI Pérez, Y Soto, C Ortíz, J Matta… - Bioorganic & medicinal …, 2015 - Elsevier
Three new ferrocene complexes were synthesized with 4-(1 H-pyrrol-1-yl) phenol group
appended to one of the Cp ring. These are: 1, 1′-4-(1H-pyrrol-1-yl) phenyl …

The redox mechanism of ferrocene and its phytochemical and biochemical compounds in anticancer therapy: A mini review

A Chaudhary, K Poonia - Inorganic Chemistry Communications, 2021 - Elsevier
Cancer is one of the most lethal diseases worldwide that endanger human health. The
persistent risk of drug-resistant cancer and the low specificity of antitumor drugs are the …

Biologically active meta-substituted ferrocenyl nitro and amino complexes: Synthesis, structural elucidation, and DFT calculations

F Asghar, A Badshah, S Fatima, S Zubair… - Journal of …, 2017 - Elsevier
In our search for new anticancer and DNA interacting drugs, ferrocene-incorporated nitro 1a-
1b and aniline compounds 2a-2b were successfully synthesized and characterized by …

(Multi) ferrocenyl five-membered heterocycles: excellent connecting units for electron transfer studies

A Hildebrandt, H Lang - Organometallics, 2013 - ACS Publications
The electro-and spectroelectrochemical behavior of diverse (multi) ferrocenyl five-
membered heterocyclic compounds, including furan, thiophene, pyrroles, phospholes, etc. is …

Functionalized ferrocenes and ferroceniums: synthesis, crystal structures and electrochemical properties based on carbazole/phenothiazine-ferrocene conjugated …

XC Wang, YP Tian, YH Kan, CY Zuo, JY Wu… - Dalton …, 2009 - pubs.rsc.org
Four new D–π–D (or D–π–D–π–D) complexes 9-ethyl-3-E-((1-ferrocenyl) vinyl)-carbazole
(1), 9-ethyl-3, 6-E, E-((1, 1-diferrocenyl) vinyl)-carbazole (2), 10-ethyl-3-E-((1-ferrocenyl) …