Lipid metabolic reprogramming is a prominent feature of clear cell renal cell carcinoma
(ccRCC). Lipid accumulation affects cellular energy homeostasis, biofilm synthesis, lipid …

Clear cell renal cell carcinoma (ccRCC) is composed of cells whose cytoplasm filled with
lipid droplets, subcellular organelles coated with adipocyte differentiation-related protein …

For clear cell renal cell carcinoma (ccRCC), lipid deposition plays important roles in the
development, metastasis, and drug resistance. However, the molecular mechanisms …

Background Renal cell carcinoma (RCC) is a clinically common tumor in the urinary system,
showing an upward trend of both incidence and mortality. Apolipoprotein C1 (APOC1) has …

The tumorigenic role and underlying mechanisms of lipid accumulation, commonly observed
in many cancers, remain insufficiently understood. In this study, we identified an AMP …

Objective The most common kidney cancer, clear cell renal cell carcinoma (ccRCC), is
closely associated with obesity. The “clear cell” variant of RCC gets its name from the large …

Renal cell carcinoma (RCC) features altered lipid metabolism and accumulated
polyunsaturated fatty acids (PUFAs). Elongation of very long–chain fatty acid (ELOVL) family …

In clear cell renal cell carcinoma (ccRCC), dysregulated lipid metabolism plays a pivotal role
in tumor initiation and progression. This study delves into the unexplored landscape of …

Background The mechanism of metabolism reprogramming is an unsolved problem in clear
cell renal cell carcinoma (ccRCC). Recently, it was discovered that the Hippo pathway …

Emerging evidence has highlighted the important role of abnormal lipid accumulation in
cancer development and progression, but the mechanism for this phenomenon remains …