American Society of Clinical Oncology Clinical Practice Guideline on uses of serum tumor markers in adult males with germ cell tumors

TD Gilligan, J Seidenfeld, EM Basch… - Journal of Clinical …, 2010 - ascopubs.org
Purpose To provide recommendations on appropriate uses for serum markers of germ cell
tumors (GCTs). Methods Searches of MEDLINE and EMBASE identified relevant studies …

Serum tumor markers in the evaluation of male germ cell tumors

LMJ Barlow, GM Badalato, JM McKiernan - Nature Reviews Urology, 2010 - nature.com
Serum tumor markers play a critical role in the diagnosis, staging, risk stratification, and
surveillance of patients with testicular germ cell tumors (GCTs). Production of the oncofetal …

Early predicted time to normalization of tumor markers predicts outcome in poor-prognosis nonseminomatous germ cell tumors

K Fizazi, S Culine, A Kramar, RJ Amato… - Journal of clinical …, 2004 - ascopubs.org
Purpose The prognostic relevance of the rate of decline of serum alpha-fetoprotein (AFP)
and human chorionic gonadotropin (HCG) during the first 3 weeks of chemotherapy for …

Serum tumour markers in testicular germ cell tumours: frequencies of elevated levels and extents of marker elevation are significantly associated with clinical …

KP Dieckmann, H Simonsen-Richter… - BioMed research …, 2019 - Wiley Online Library
Introduction. Although serum tumor markers beta human chorionic gonadotropin (bHCG),
alpha‐fetoprotein (AFP), and lactate dehydrogenase (LDH) are well‐established tools for …

Serum tumor marker half-life during chemotherapy allows early prediction of complete response and survival in nonseminomatous germ cell tumors

GC Toner, NL Geller, C Tan, J Nisselbaum, GJ Bosl - Cancer research, 1990 - AACR
The prognostic value and therapeutic utility of monitoring the decay of α-fetoprotein (AFP)
and human chorionic gonadotropin (HCG) after chemotherapy for nonseminomatous germ …

Testicular cancer biomarkers: a role for precision medicine in testicular cancer

R Leão, AE Ahmad, RJ Hamilton - Clinical genitourinary cancer, 2019 - Elsevier
Testicular germ cell tumors (TGCTs) represent the most common solid tumors among men
aged 15 to 34 years. Fortunately, recent advances have made testicular cancer a highly …

Predicting outcome to chemotherapy in patients with germ cell tumors: the value of the rate of decline of human chorionic gonadotrophin and alpha-fetoprotein during …

M Mazumdar, DF Bajorin, J Bacik, G Higgins… - Journal of clinical …, 2001 - ascopubs.org
PURPOSE: The prognostic significance of the rate of decline of the serum tumor marker
alpha-fetoprotein (AFP) and human chorionic gonadotrophin (HCG) during the first two …

The present and future of serum diagnostic tests for testicular germ cell tumours

MJ Murray, RA Huddart, N Coleman - Nature Reviews Urology, 2016 - nature.com
Testicular germ cell tumours (GCTs) are the most common malignancy occurring in young
adult men and the incidence of these tumours is increasing. Current research priorities in …

Serum tumor marker decline is an early predictor of treatment outcome in germ cell tumor patients treated with cisplatin and ifosfamide salvage chemotherapy

BA Murphy, RJ Motzer, M Mazumdar, V Vlamis… - Cancer, 1994 - Wiley Online Library
Background. Serum tumor marker regression (alpha‐fetoprotein [AFP] and human chorionic
gonadotrophin [hCG]) was studied in patients treated with ifosfamide‐based chemotherapy …

Testicular cancer, version 2.2015

RJ Motzer, E Jonasch, N Agarwal, C Beard… - Journal of the National …, 2015 - jnccn.org
Germ cell tumors (GCTs) account for 95% of testicular cancers. Testicular GCTs constitute
the most common solid tumor in men between the ages of 20 and 34 years, and the …