Nitric oxide (NO) is a potent vasodilator that was initially described as the mediator of
endothelium-dependent relaxation (endothelium-derived relaxing factor, EDRF). It is now …

Nitrogen monoxide (NO) has recently emerged as an important mediator of cellular and
molecular events which impacts the pathophysiology of cerebral ischemia. Although …

Nitric oxide (NO) has only recently been appreciated as a normal biologic substance with a
role in signal transduction. It was first identified as endothe lial-derived relaxing factor in …

There is increasing evidence that nitric oxide (NO) is an important molecular messenger
involved in a wide variety of biological processes. Recent data suggest that NO is also …

The proposal that nitric oxide (NO) or its reactant products mediate toxicity in brain remains
controversial in part because of the use of nonselective agents that block NO formation in …

NO satisfies many criteria for a neuronal messenger molecule in both the central and
peripheral nervous sy~ tem.~~,~ NO was first identified as endothelium-derived relaxing …

Mechanisms that regulate the cerebral circulation have been intensively investigated in
recent years. The role of several vasodilator mechanisms has been examined in the …

The presence of a cholinergic vasodilator innervation to cerebral circulation is well
established. Despite its high endogenous concentration in cerebral blood vessels …

Nitric oxide (NO) plays an important role in the pathogenesis of neuronal injury during
cerebral ischemia. The endothelial and neuronal isoforms of nitric oxide synthase (eNOS …

Nitric oxide (NO) is undoubtedly quite an important intercellular messenger in cerebral and
peripheral hemodynamics. This molecule, formed by constitutive isomers of NO synthase …