Loneliness and Risk of Parkinson Disease

A Terracciano, M Luchetti, S Karakose… - JAMA …, 2023 - jamanetwork.com
Importance Loneliness is associated with morbidity and mortality, including higher risk of
neurodegenerative diseases. To our knowledge, no study has examined whether the …

The impact of loneliness on quality of life in people with Parkinson's disease: results from the Survey of Health, Ageing and Retirement in Europe

T Prell, A Schönenberg, KG Heimrich - Frontiers in Medicine, 2023 - frontiersin.org
Background Loneliness is a growing issue for public health in an aging society. However,
there is a lack of research on loneliness in people with Parkinson's disease (PwPD) …

The plight of loneliness in Parkinson's disease: New opportunities

DA González, MH de Siqueira Tosin… - Parkinsonism & Related …, 2022 - Elsevier
The human phenomenon of loneliness has been increasing in prominence across societies,
with precipitous increase since COVID-19, and individuals with Parkinson's disease are not …

Loneliness as a risk factor for dementia and other adverse health outcomes: Commentary on “Loneliness and risk of all-cause, Alzheimer's, vascular, and …

PJ Na, YY Lim, RH Pietrzak - International Psychogeriatrics, 2023 - cambridge.org
Loneliness is defined as subjective distress resulting from a less than desired level of social
connectedness (Hawkley and Cacioppo, 2010). The deleterious effects of loneliness on a …

Chronic loneliness and the risk of incident stroke in middle and late adulthood: a longitudinal cohort study of US older adults

Y Soh, I Kawachi, LD Kubzansky, LF Berkman… - …, 2024 - thelancet.com
Background Loneliness has been implicated as a stroke risk factor, yet studies have
examined loneliness at only one time point. The association of loneliness changes and risk …

A meta-analysis of loneliness and risk of dementia using longitudinal data from> 600,000 individuals

M Luchetti, D Aschwanden, AA Sesker, X Zhu… - Nature Mental …, 2024 - nature.com
Loneliness is one critical risk factor for cognitive health. Here we combined data from
ongoing aging studies and the published literature and provide the largest meta-analysis on …

Association of loneliness with 10-year dementia risk and early markers of vulnerability for neurocognitive decline

J Salinas, AS Beiser, JK Samra, A O'Donnell… - Neurology, 2022 - AAN Enterprises
Background and Objectives Loneliness is common, and its prevalence is rising. The
relationship of loneliness with subsequent dementia and the early preclinical course of …

Associations of loneliness with risk of Alzheimer's disease dementia in the Framingham Heart Study

SC Akhter‐Khan, Q Tao, TFA Ang… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction The relationship between persistent loneliness and Alzheimer's disease (AD) is
unclear. We examined the relationship between different types of mid‐life loneliness and the …

Association between loneliness and dementia risk: A systematic review and meta-analysis of cohort studies

L Qiao, G Wang, Z Tang, S Zhou, J Min… - Frontiers in Human …, 2022 - frontiersin.org
Loneliness has been reported to be associated with an increased risk of dementia; however,
the extent of this relationship remains controversial. This study aimed to assess the strength …

Loneliness and risk of all-cause, Alzheimer's, vascular, and frontotemporal dementia: a prospective study of 492,322 individuals over 15 years

AR Sutin, M Luchetti, D Aschwanden, X Zhu… - International …, 2023 - cambridge.org
Objectives: This study examined the association between loneliness and risk of incident all-
cause dementia and whether the association extends to specific causes of dementia …