Objective: The aim of the study was to evaluate possible new treatments for major
depressive disorder in patients with comorbid alcohol dependence in a municipal alcohol …

Background Alcohol dependence comorbid with major depressive disorder poses a major
challenge in the clinical setting. The results in the treatment with selective serotonin re …

Major depressive disorder and alcohol dependence are common and serious mental
illnesses. There is a great interest in discovering useful treatments for both mood symptoms …

Objective Studies indicate that serotoninergic and noradrenergic pathophysiological
mechanisms may underlie both alcohol abuse/dependence and depressive disorder. The …

Background: Depressive disorders are commonly comorbid with alcoholism, particularly in
treatmentseeking samples. If antidepressant treatment were safe and improved the …

Background: There is growing evidence that N‐methyl‐d‐aspartate (NMDA) receptor
antagonists may have potential for the treatment of alcohol disorders. Memantine is a …

Objective Geriatric depression is difficult to treat and frequently accompanied by cognitive
complaints that increase risk for dementia. New treatment strategies targeting both …

Depression Associated with Alcohol Withdrawal; Imipramine Therapy Compared with Placebo
Page 1 Quart. J. Stud. Ale. 32: 343-348, 1971 The informative abstract of this article is in Part B …

ContextDepression and substance abuse are common and costly disorders that frequently
co-occur, but controversy about effective treatment for patients with both disorders persists …

There is compelling evidence that alcohol-induced neurotoxicity is related to glutamate
excitotoxicity. It was hypothesized that the low-affinity NMDA receptor antagonist memantine …