The eukaryotic initiation factor 4E (eIF4E) plays a pivotal role in the control of protein
synthesis. eIF4E binds to the mRNA 5′ cap structure, m7GpppN (where N is any …

In eukaryotes, a key step in the initiation of translation is the binding of the eukaryotic
initiation factor 4E (eIF4E) to the cap structure of the mRNA. Subsequent recruitment of …

The emerging field of nuclear eIF research has yielded many surprises and led to the
dissolution of some dogmatic/ideological viewpoints of the place of translation in the …

All eukaryotic cellular mRNAs (except organellar) possess at their 5 'end the structure
m7GpppX (where X is any nucleotide) termed the" cap." The cap structure facilitates the …

Eukaryotic initiation factor 4E (eIF4E) is the subunit of eIF4F that binds to the cap structure at
the 5′ end of messenger RNA and is a critical component for the regulation of translation …

Eukaryotic initiation factor (eIF) 4B is part of the protein complex involved in the recognition
and binding of mRNA to the ribosome. DrosophilaeIF4B is a single‐copy gene that encodes …

Eukaryotic protein synthesis initiation factor 4E (eIF-4E) is a 25-kDa polypeptide that binds to
the 7-methylguanosine-containing cap of mRNA and participates in the transfer of mRNA to …

Recruitment of mRNA to the 40S ribosomal subunit requires the coordinated interaction of a
large number of translation initiation factors. In mammals, the direct interaction between …

A common feature of viral infection is the subversion of the host cell machinery towards the
preferential translation of viral products. In some instances, this is partly mediated by the …

Eukaryotic initiation factor (eIF) 2B catalyzes a key regulatory step in the initiation of mRNA
translation. eIF2B is well characterized in mammals and in yeast, although little is known …