Investigating the potential anti-SARS-CoV-2 and anti-MERS-CoV activities of yellow necklacepod among three selected medicinal plants: extraction, isolation …

HI Abd-Alla, O Kutkat, HM Sweelam, WM Eldehna… - Metabolites, 2022 - mdpi.com
The anti-MERS-CoV activities of three medicinal plants (Azadirachta indica, Artemisia
judaica, and Sophora tomentosa) were evaluated. The highest viral inhibition percentage …

Bioactive Components of Myracrodruon urundeuva against SARS-CoV-2: A Computational Study

SKS Alves, CS Sousa, EKA Viana, HCA Souza… - Drugs and Drug …, 2023 - mdpi.com
SARS-CoV-2 (severe acute respiratory distress syndrome coronavirus 2) is the causative
agent for the novel coronavirus disease 2019 (COVID-19). It raises serious biosecurity …

Identification of natural products inhibiting SARS-CoV-2 by targeting viral proteases: a combined in silico and in vitro approach

A Wasilewicz, B Kirchweger, D Bojkova… - Journal of Natural …, 2023 - ACS Publications
In this study, an integrated in silico–in vitro approach was employed to discover natural
products (NPs) active against SARS-CoV-2. The two SARS-CoV-2 viral proteases, ie, main …

Dual SARS-CoV-2 and MERS-CoV inhibitors from Artemisia monosperma: isolation, structure elucidation, molecular modelling studies, and in vitro activities

AM Badawy, MSM Donia, NG Hamdy… - Organic & …, 2024 - pubs.rsc.org
The COVID-19 pandemic has spread throughout the whole globe, so it is imperative that all
available resources be used to treat this scourge. In reality, the development of new …

Screening of natural products inhibitors of SARS-CoV-2 entry

P González-Maldonado, N Alvarenga… - Molecules, 2022 - mdpi.com
The COVID-19 pandemic has led to the search for new molecules with antiviral activity
against SARS-CoV-2. The entry of the virus into the cell is one of the main targets for …

[PDF][PDF] Herbal compounds from Syzygium aromaticum and Cassia acutifolia as a shield against SARS-CoV-2 Mpro: A molecular docking approach

G Yunus - Biointerface Res. Appl. Chem, 2021 - biointerfaceresearch.com
Novel coronavirus (severe acute respiratory syndrome coronavirus 2; SARS-CoV-2) was first
identified in China in December 2019. Currently, the novel coronavirus disease 2019 …

Identification of SARS-CoV-2 spike protein inhibitors from Urtica dioica to develop herbal-based therapeutics against COVID-19

S Upreti, JS Prusty, A Kumar… - World Journal of …, 2023 - journals.lww.com
Objective: The high transmission rate and mutations of SARS-CoV-2 have made it a global
pandemic, and the shortage of any effective clinical treatment has created such a …

Antiviral phytocompounds “ellagic acid” and “(+)-sesamin” of Bridelia retusa identified as potential inhibitors of SARS-CoV-2 3CL pro using extensive molecular …

AK Umar, JH Zothantluanga, K Aswin, S Maulana… - Structural …, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected billions and
has killed millions to date. Studies are being carried out to find therapeutic molecules that …

In silico identification of natural products from Centella asiatica as severe acute respiratory syndromecoronavirus 2 main protease inhibitor

PG Maya, W Mahayasih, I Ahmad - Journal of Advanced …, 2021 - journals.lww.com
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) main protease (S-CoV-2
Mpro) is one of the main targets in designing antiviral against SARS-CoV-2. Centella …

Flavonoids in Ampelopsis grossedentata as covalent inhibitors of SARS-CoV-2 3CLpro: Inhibition potentials, covalent binding sites and inhibitory mechanisms

Y Xiong, GH Zhu, YN Zhang, Q Hu, HN Wang… - International Journal of …, 2021 - Elsevier
Abstract Coronavirus 3C-like protease (3CL pro) is a crucial target for treating coronavirus
diseases including COVID-19. Our preliminary screening showed that Ampelopsis …