Musculoskeletal pain conditions are age-related, leading contributors to chronic pain and
pain-related disability, which are expected to rise with the rapid global population aging …

Osteoarthritis (OA) is a major cause of pain and physical disability in adults, and an
increasingly common disease given its associations with aging and a growing …

Chronic pain is a significant public health burden. Several international guidelines and
influential reviews recommend the use of paracetamol (acetaminophen) as the first-line …

Acute pain is among the most common reasons that people consult primary care physicians,
who must weigh benefits versus risks of analgesics use for each patient. Paracetamol …

Objective To evaluate the efficacy and safety of paracetamol as an analgesic medication in a
range of painful conditions. Study design Systematic review of systematic reviews of the …

Paracetamol (acetaminophen) is one of the most widely used of all drugs, with a wealth of
experience clearly establishing it as the standard antipyretic and analgesic for mild to …

Background Ibuprofen and paracetamol have long been used as analgesics in a range of
acute, intermittent and chronic pain conditions. Paracetamol is often the first line analgesic …

Paracetamol (acetaminophen) is the most commonly used drug in the world, with a long
record of use in acute and chronic pain. In recent years, the benefits of paracetamol use in …

Objective To investigate the efficacy and safety of paracetamol (acetaminophen) in the
management of spinal pain and osteoarthritis of the hip or knee. Design Systematic review …

Paracetamol is an important drug in the armoury of the acute pain clinician, yet many of us
know little of its pharmacodynamics and pharmacokinetics. In this review we discuss the …