Regenerative processes occurring under physiological (maintenance) and pathological
(reparative) conditions are a fundamental part of life and vary greatly among different …

Systemic or intracerebral delivery of neural stem and progenitor cells (NSPCs) and
activation of endogenous NSPCs hold much promise as potential treatments for diseases in …

The pharmacological support and stimulation of endogenous and transplanted neural stem
cells (NSCs) is a major challenge in brain repair. Trauma to the central nervous system …

Stem cell technology is a promising branch of regenerative medicine that is aimed at
developing new approaches for the treatment of severely debilitating human diseases …

After an ischemic stroke, neural precursor cells (NPCs) proliferate within major germinal
niches of the brain. Endogenous NPCs subsequently migrate toward the ischemic lesion …

Spontaneous neural tissue repair occurs in patients affected by inflammatory and
degenerative disorders of the central nervous system (CNS). However, this process is not …

Compelling evidence exists that neural stem cell-based therapies protect the central
nervous system (CNS) from chronic inflammatory degeneration, such as that occurring in …

The physiological and pathological properties of the neural germinal stem cell niche have
been well-studied in the past 30 years, mainly in animals and within given limits in humans …

Compelling evidence from experimental animal disease models and early-phase clinical
trials identifies the transplantation of neural progenitor/stem cells (NSCs) as a viable path …

The irreversible loss of function after axonal injury in the central nervous system (CNS) is a
result of the lack of neurogenesis, poor regeneration, and the spread of damage caused by …