Radiation-induced pneumonitis and fibrosis are dose-limiting side effects of thoracic
irradiation. Thoracic irradiation triggers acute and chronic environmental lung changes that …

BACKGROUND AND PURPOSE: Pneumonitis and fibrosis constitute dose-limiting side
effects of thorax or total body irradiation. An improved understanding of the underlying …

Delivery of high doses of radiation to thoracic region, particularly with non-small cell lung
cancer patients, becomes difficult due to subsequent complications arising in the lungs of …

Background Lymphocyte infiltration is a common feature of radiation-induced pneumonitis
and fibrosis, but their contribution to the pathogenic processes is still unclear. Here, we …

Radiation therapy is one of the most common treatment strategies for thorax malignancies.
One of the considerable limitations of this therapy is its toxicity to normal tissue. The lung is …

There is compelling evidence that lymphocytes are a recurring feature in radiation damaged
normal tissues, but assessing their functional significance has proven difficult. Contradictory …

Exposure of the lung to radiation produces injury and inflammatory responses that result in
microenvironmental alterations, which can promote the development of pneumonitis and/or …

The body senses “danger” from “damaged self” molecules through members of the same
receptor superfamily it uses for microbial “non-self”, triggering canonical signaling pathways …

Purpose: In our ongoing investigation into the consequences of a radiological terrorism or
nuclear dispersion event, we assessed whether a dose range that is believed to be sub …

International Symposium on Radiation-Induced Lung Damage includes activation of
lymphocytes and probably diÚ erent cytokine cascades (Morgan and Breit 1995).(Dresden …