Almost all mammalian cell types have morphologies that are uniquely tailored to their
physiological functions. This immense variation in cell shape depends on an underlying …

Podocytes exhibit a unique cytoskeletal architecture that is fundamentally linked to their
function in maintaining the kidney filtration barrier. The cytoskeleton regulates podocyte …

Podocytes of the renal glomerulus are unique cells with a complex cellular organization
consisting of a cell body, major processes and foot processes. Podocyte foot processes form …

Background: Podocyte biology is a developing science that promises to help improve
understanding of the mechanistic nature of multiple diseases associated with proteinuria …

Glomerular injury often incites a progression to chronic kidney disease, which affects
millions of patients worldwide. Despite our current understanding of this disease's …

Genetic studies of hereditary forms of nephrotic syndrome have identified several proteins
that are involved in regulating the permselective properties of the glomerular filtration …

Glomerular visceral epithelial cells, also known as podocytes, are highly specialized
epithelial cells that cover the outer layer of the glomerular basement membrane. Podocytes …

The visceral glomerular epithelial cell, also known as the podocyte, plays an important role
in the maintenance of renal glomerular function. This cell type is highly specialized and its …

Podocytes form an epithelial layer on the outer aspect of the basement membrane of
glomerular capillaries. The interdigitating pattern of podocyte foot processes (PFPs) …

Podocytes are an integral part of the glomerular filtration barrier, a structure that prevents
filtration of large proteins and macromolecules into the urine. Podocyte function is …