Acetylcholinesterase inhibitors: pharmacology and toxicology

MB Colovic, DZ Krstic… - Current …, 2013 - ingentaconnect.com
Acetylcholinesterase is involved in the termination of impulse transmission by rapid
hydrolysis of the neurotransmitter acetylcholine in numerous cholinergic pathways in the …

[HTML][HTML] Acetylcholinesterase inhibitors: pharmacology and toxicology

MB Čolović, DZ Krstić, TD Lazarević-Pašti… - Current …, 2013 - ncbi.nlm.nih.gov
Acetylcholinesterase is involved in the termination of impulse transmission by rapid
hydrolysis of the neurotransmitter acetylcholine in numerous cholinergic pathways in the …

Acetylcholinesterase inhibitors: a patent review (2008–present)

M Pohanka - Expert opinion on therapeutic patents, 2012 - Taylor & Francis
Introduction: Both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are
present in the body in large amounts. AChE is an important part of the cholinergic nervous …

[PDF][PDF] Structural requirements of acetylcholinesterase reactivators

K Kuca, D Jun, K Musilek - Mini reviews in medicinal chemistry, 2006 - researchgate.net
Nerve agents (sarin, soman, cyclosarin, tabun and VX agent) and pesticides (paraoxon,
chlorpyrifos, TEPP) represent extremely toxic group of organophosphorus compounds …

Modulators of acetylcholinesterase activity: From Alzheimer's disease to anti-cancer drugs

T Lazarevic-Pasti, A Leskovac, T Momic… - Current medicinal …, 2017 - ingentaconnect.com
Background: Acetylcholinesterase (AChE) is involved in the termination of impulse
transmission by rapid hydrolysis of the neurotransmitter acetylcholine in numerous …

The state of the art on acetylcholinesterase inhibitors in the treatment of Alzheimer's disease

I Vecchio, L Sorrentino, A Paoletti… - Journal of Central …, 2021 - journals.sagepub.com
Alzheimer's disease (AD) is a chronic disabling disease that affects the central nervous
system. The main consequences of AD include the decline of cognitive functions and …

Mechanism of action of organophosphorus and carbamate insecticides.

TR Fukuto - Environmental health perspectives, 1990 - ehp.niehs.nih.gov
Organophosphorus and carbamate insecticides are toxic to insects and mammals by virtue
of their ability to inactivate the enzyme acetylcholinesterase. This review addresses the …

[图书][B] Organophosphorus poisons: anticholinesterases and related compounds

DF Heath - 2013 - books.google.com
Modern Trends in Physiological Sciences, Volume 13: Organophosphorus Poisons:
Anticholinesterases and Related Compounds covers the reactions, toxic action, activation …

Acetylcholinesterase inhibition in Alzheimer's Disease

B Ibach, E Haen - Current Pharmaceutical Design, 2004 - ingentaconnect.com
Alzheimer's Disease (AD) is the most common cause for dementia in our ageing population,
which leads to a slowly progressive, irretrievable ruination of mental function. The …

A critical review of cholinesterase inhibitors as a treatment modality in Alzheimer's disease

L S. Schneider - Dialogues in clinical neuroscience, 2000 - Taylor & Francis
Early research into Alzheimer's disease launched the cholinergic hypothesis, based on the
correlation between central cholinergic deficiency and clinical measures of cognitive …