Injectable pH thermo-responsive hydrogel scaffold for tumoricidal neural stem cell therapy for glioblastoma multiforme
JL King, P Maturavongsadit, SD Hingtgen… - Pharmaceutics, 2022 - mdpi.com
Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults and
despite recent advances in treatment modalities, GBM remains incurable. Injectable …
despite recent advances in treatment modalities, GBM remains incurable. Injectable …
Thermosensitive composite hydrogel incorporated with curcumin-loaded nanopolymersomes for prolonged and localized treatment of glioma
In the current study, in order to augment the therapeutic efficacy of curcumin, thermo-
sensitive biodegradable hydrogel composed of poly (ε-caprolactone-co-lactide)-b-poly …
sensitive biodegradable hydrogel composed of poly (ε-caprolactone-co-lactide)-b-poly …
Three‐dimensional biomimetic hyaluronic acid hydrogels to investigate glioblastoma stem cell behaviors
Glioblastoma multiforme (GBM) is the deadliest form of primary brain tumor. GBM tumors are
highly heterogeneous, being composed of tumor cells as well as glioblastoma stem cells …
highly heterogeneous, being composed of tumor cells as well as glioblastoma stem cells …
Dual-drug loaded nanomedicine hydrogel as a therapeutic platform to target both residual glioblastoma and glioma stem cells
Glioblastoma (GBM) recurrences are inevitable, and mainly originate from residual tumor
cells and the presence of glioma stem cells (GSC) around the resection cavity borders. We …
cells and the presence of glioma stem cells (GSC) around the resection cavity borders. We …
Development of a Synthetic, Injectable Hydrogel to Capture Residual Glioblastoma and Glioblastoma Stem‐Like Cells with CXCL12‐Mediated Chemotaxis
Glioblastoma (GBM), characterized by high infiltrative capacity, is the most common and
deadly type of primary brain tumor in adults. GBM cells, including therapy‐resistant …
deadly type of primary brain tumor in adults. GBM cells, including therapy‐resistant …
Intratumoral injection of hydrogel-embedded nanoparticles enhances retention in glioblastoma
Intratumoral drug delivery is a promising approach for the treatment of glioblastoma
multiforme (GBM). However, drug washout remains a major challenge in GBM therapy. Our …
multiforme (GBM). However, drug washout remains a major challenge in GBM therapy. Our …
Characterization and structure-property relationships of an injectable thiol-Michael addition hydrogel toward compatibility with glioblastoma therapy
Glioblastoma multiforme (GBM) is an aggressive primary brain cancer and although patients
undergo surgery and chemoradiotherapy, residual cancer cells still migrate to healthy brain …
undergo surgery and chemoradiotherapy, residual cancer cells still migrate to healthy brain …
Glioblastoma spheroid growth and chemotherapeutic responses in single and dual-stiffness hydrogels
J Bruns, T Egan, P Mercier, SP Zustiak - Acta Biomaterialia, 2023 - Elsevier
Glioblastoma (GBM) is the deadliest brain tumor for which there is no cure. Bioengineered
GBM models, such as hydrogel-encapsulated spheroids, that capture both cell-cell and cell …
GBM models, such as hydrogel-encapsulated spheroids, that capture both cell-cell and cell …
Polymeric biomaterial scaffolds for tumoricidal stem cell glioblastoma therapy
KM Moore, AB Murthy, EG Graham-Gurysh… - ACS biomaterials …, 2020 - ACS Publications
Glioblastoma (GBM) is the most common primary brain tumor and has a poor prognosis; as
such, there is an urgent need to develop innovative new therapies. Tumoricidal stem cells …
such, there is an urgent need to develop innovative new therapies. Tumoricidal stem cells …
Nano composite thermo-sensitive gel for paclitaxel and temozolomide co-delivery to glioblastoma cells
Y Xu, M Shen, Y Sun, P Gao… - Journal of Nanoscience …, 2016 - ingentaconnect.com
In this work, we have reported the preparation and optimization of paclitaxel (PTX) and
temozolomide (TMZ) loaded monomethoxy (polyethylene glycol)-poly (D, L-lactide-co …
temozolomide (TMZ) loaded monomethoxy (polyethylene glycol)-poly (D, L-lactide-co …