UFMylation: a unique & fashionable modification for life
Y Wei, X Xu - Genomics, Proteomics and Bioinformatics, 2016 - academic.oup.com
Abstract Ubiquitin-fold modifier 1 (UFM1) is one of the newly-identified ubiquitin-like
proteins. Similar to ubiquitin, UFM1 is conjugated to its target proteins by a three-step …
proteins. Similar to ubiquitin, UFM1 is conjugated to its target proteins by a three-step …
A novel type of E3 ligase for the Ufm1 conjugation system
K Tatsumi, Y Sou, N Tada, E Nakamura… - Journal of Biological …, 2010 - ASBMB
The ubiquitin fold modifier 1 (Ufm1) is the most recently discovered ubiquitin-like modifier
whose conjugation (ufmylation) system is conserved in multicellular organisms. Ufm1 is …
whose conjugation (ufmylation) system is conserved in multicellular organisms. Ufm1 is …
Decrypting UFMylation: how proteins are modified with UFM1
Besides ubiquitin (Ub), humans have a set of ubiquitin-like proteins (UBLs) that can also
covalently modify target proteins. To date, less is known about UBLs than Ub and even less …
covalently modify target proteins. To date, less is known about UBLs than Ub and even less …
UFMylation system: an emerging player in tumorigenesis
Y Jing, Z Mao, F Chen - Cancers, 2022 - mdpi.com
Simple Summary The ubiquitin-fold modifier 1 (UFM1) is a newly identified post-translational
modification protein that has been implicated in multiple cellular processes and diseases …
modification protein that has been implicated in multiple cellular processes and diseases …
UFMylation: a ubiquitin-like modification
X Zhou, SJ Mahdizadeh, M Le Gallo… - Trends in Biochemical …, 2024 - cell.com
Post-translational modifications (PTMs) add a major degree of complexity to the proteome
and are essential controllers of protein homeostasis. Amongst the hundreds of PTMs …
and are essential controllers of protein homeostasis. Amongst the hundreds of PTMs …
A guide to UFMylation, an emerging posttranslational modification
Ubiquitin Fold Modifier‐1 (UFM1) is a ubiquitin‐like modifier (UBL) that is posttranslationally
attached to lysine residues on substrates via a dedicated system of enzymes conserved in …
attached to lysine residues on substrates via a dedicated system of enzymes conserved in …
A novel protein‐conjugating system for Ufm1, a ubiquitin‐fold modifier
M Komatsu, T Chiba, K Tatsumi, S Iemura… - The EMBO …, 2004 - embopress.org
Several studies have addressed the importance of various ub iquitin‐l ike (UBL) post‐
translational modifiers. These UBLs are covalently linked to most, if not all, target protein (s) …
translational modifiers. These UBLs are covalently linked to most, if not all, target protein (s) …
Crystal structure of Ufc1, the Ufm1-conjugating enzyme
T Mizushima, K Tatsumi, Y Ozaki, T Kawakami… - Biochemical and …, 2007 - Elsevier
Ubiquitin and ubiquitin-like protein-conjugating enzymes play central roles in
posttranslational modification processes. The ubiquitin-fold modifier 1 (Ufm1), one of a …
posttranslational modification processes. The ubiquitin-fold modifier 1 (Ufm1), one of a …
NMR and X-RAY structures of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1 …
G Liu, F Forouhar, A Eletsky, HS Atreya… - Journal of structural and …, 2009 - Springer
For cell regulation, E2-like ubiquitin-fold modifier conjugating enzyme 1 (Ufc1) is involved in
the transfer of ubiquitin-fold modifier 1 (Ufm1), a ubiquitin like protein which is activated by …
the transfer of ubiquitin-fold modifier 1 (Ufm1), a ubiquitin like protein which is activated by …
The post-translational role of UFMylation in physiology and disease
X Wang, X Xu, Z Wang - Cells, 2023 - mdpi.com
Ubiquitin-fold modifier 1 (UFM1) is a newly identified ubiquitin-like protein that has been
conserved during the evolution of multicellular organisms. In a similar manner to ubiquitin …
conserved during the evolution of multicellular organisms. In a similar manner to ubiquitin …