[HTML][HTML] Cognitive control deficits in schizophrenia: mechanisms and meaning
Although schizophrenia is an illness that has been historically characterized by the
presence of positive symptomatology, decades of research highlight the importance of …
presence of positive symptomatology, decades of research highlight the importance of …
Systemic hypotheses for generalized cognitive deficits in schizophrenia: a new take on an old problem
D Dickinson, PD Harvey - Schizophrenia bulletin, 2009 - academic.oup.com
The schizophrenia research community, including government, industry, and academia, has
made development of procognitive treatment strategies a priority. Much current research is …
made development of procognitive treatment strategies a priority. Much current research is …
Cognition in schizophrenia: core psychological and neural mechanisms
The challenge in understanding cognitive impairment in schizophrenia is that people with
this illness have deficits in an array of domains. Here, we briefly review evidence regarding …
this illness have deficits in an array of domains. Here, we briefly review evidence regarding …
[HTML][HTML] Proactive and reactive cognitive control and dorsolateral prefrontal cortex dysfunction in first episode schizophrenia
Cognitive control deficits have been consistently documented in patients with schizophrenia.
Recent work in cognitive neuroscience has hypothesized a distinction between two …
Recent work in cognitive neuroscience has hypothesized a distinction between two …
[HTML][HTML] Executive function, neural circuitry, and genetic mechanisms in schizophrenia
DP Eisenberg, KF Berman - Neuropsychopharmacology, 2010 - nature.com
After decades of research aimed at elucidating the pathophysiology and etiology of
schizophrenia, it has become increasingly apparent that it is an illness knowing few …
schizophrenia, it has become increasingly apparent that it is an illness knowing few …
[HTML][HTML] Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment
RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …
functioning associated with the disorder and are not responsive to existing treatments. In this …
Cognitive deficits and functional outcome in schizophrenia
Cognitive dysfunction is a core feature of schizophrenia. Deficits are moderate to severe
across several domains, including attention, working memory, verbal learning and memory …
across several domains, including attention, working memory, verbal learning and memory …
Neural correlates of cognitive deficits across developmental phases of schizophrenia
Schizophrenia is associated with cognitive deficits across all stages of the illness (ie, high
risk, first episode, early and chronic phases). Identifying the underlying neurobiological …
risk, first episode, early and chronic phases). Identifying the underlying neurobiological …
Association of dorsolateral prefrontal cortex dysfunction with disrupted coordinated brain activity in schizophrenia: relationship with impaired cognition, behavioral …
Objective: Although deficits in cognitive control are thought to contribute to the diverse
cognitive and behavioral abnormalities in individuals with schizophrenia, the neural …
cognitive and behavioral abnormalities in individuals with schizophrenia, the neural …
Translating the basic and clinical cognitive neuroscience of schizophrenia to drug development and clinical trials of antipsychotic medications
MF Green, DL Braff - Biological psychiatry, 2001 - Elsevier
Neurocognitive deficits have become increasingly important defining features of
schizophrenia and its treatment. Multiple domains of neurocognitive functions are impaired …
schizophrenia and its treatment. Multiple domains of neurocognitive functions are impaired …