A major challenge in drug delivery is the internalization through the apical plasma
membrane of the polarized epithelial cells lining organs facing the external environment, eg …

Polymeric nanoparticles have tremendous potential either as carriers or markers in
treatment for diseases or as diagnostics in biomedical applications. Finding the optimal …

Nanoparticles and their interaction with human cells have been a focus of many groups
during the past decade. We discuss and review here the progress in the field of …

The aim of this study was to evaluate the uptake mechanism of thiolated nanostructured lipid
carriers (NLCs). NLCs were decorated with a short-chain polyoxyethylene (10) stearyl ether …

Nanoparticles may address challenges by human diseases through improving diagnosis,
vaccination and treatment. The uptake mechanism regulates the type of threat a particle …

Epithelial cell membranes as the typical biological barrier constitute the prime obstacle for
the transport of therapeutic agents including nanomedicines. The previous studies on the …

The endocytotic mechanisms involved in the uptake of charged polystyrene nanoparticles
into HeLa cells were investigated. Uptake experiments were done in the presence or …

Nanoparticle capture and elimination by the immune system are great obstacles for drug
delivery. Camouflaging nanoparticles with cell membrane represents a promising strategy to …

Precise knowledge regarding cellular uptake of nanoparticles is of great importance for
future biomedical applications. Four different endocytotic uptake mechanisms, that is …

Polymeric nanoparticles have demonstrated enormous potential as cellular drug delivery
vehicles. Nanoparticles improve drug's stability as well as its availability and retention at the …