High-resolution label-free imaging of tissue morphology with confocal phase microscopy

M Schnell, S Gupta, TP Wrobel, MG Drage, R Bhargava… - Optica, 2020 - opg.optica.org
Label-free imaging approaches seek to simplify and augment histopathologic assessment
by replacing the current practice of staining by dyes to visualize tissue morphology with …

Fast Fourier ptychographic quantitative phase microscopy for in vitro label-free imaging

R Wu, Z Luo, M Liu, H Zhang, J Zhen, L Yan… - Biomedical Optics …, 2024 - opg.optica.org
Quantitative phase microscopy (QPM) is indispensable in biomedical research due to its
advantages in unlabeled transparent sample thickness quantification and obtaining …

Quantitative phase imaging for medical diagnosis

H Majeed, S Sridharan, M Mir, L Ma, E Min… - Journal of …, 2017 - Wiley Online Library
Optical microscopy is an indispensable diagnostic tool in modern healthcare. As a prime
example, pathologists rely exclusively on light microscopy to investigate tissue morphology …

[HTML][HTML] Adaptive optical quantitative phase imaging based on annular illumination Fourier ptychographic microscopy

Y Shu, J Sun, J Lyu, Y Fan, N Zhou, R Ye, G Zheng… - PhotoniX, 2022 - Springer
Quantitative phase imaging (QPI) has emerged as a valuable tool for biomedical research
thanks to its unique capabilities for quantifying optical thickness variation of living cells and …

[HTML][HTML] Capturing cell morphology dynamics with high temporal resolution using single-shot quantitative phase gradient imaging

SW Hur, M Kwon, R Manoharaan… - Journal of Biomedical …, 2024 - ncbi.nlm.nih.gov
Significance Label-free quantitative phase imaging can potentially measure cellular
dynamics with minimal perturbation, motivating efforts to develop faster and more sensitive …

Quantitative phase imaging with epi-mode illumination for fiber-optic endoscopy

Z Guang, PB Ledwig, PC Costa… - … Phase Imaging VI, 2020 - spiedigitallibrary.org
Quantitative phase imaging (QPI) provides unique access to cellular and subcellular
structures with nanometer-scale sensitivity, making it a valuable tool for non-destructive …

Quantitative phase imaging: recent advances and expanding potential in biomedicine

TL Nguyen, S Pradeep, RL Judson-Torres, J Reed… - ACS …, 2022 - ACS Publications
Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

[HTML][HTML] Beyond fluorescence: advances in computational label-free full specificity in 3D quantitative phase microscopy

D Pirone, V Bianco, L Miccio, P Memmolo… - Current Opinion in …, 2024 - Elsevier
Highlights•Label-free QPI can overcome the specificity gap over fluorescence microscopy
(FM).•The specificity in QPI can be achieved from 2D phase maps or 3D RI tomograms.•2D …

Implementation of a portable diffraction phase microscope for digital histopathology

N Aimakov, E Min, S Ban, S Lee, JK Bae… - Journal of …, 2024 - Wiley Online Library
Quantitative phase imaging (QPI) has a significant advantage in histopathology as it helps in
differentiating biological tissue structures and cells without the need for staining. To make …

Quantitative phase imaging in biomedicine

YK Park, C Depeursinge, G Popescu - Nature photonics, 2018 - nature.com
Quantitative phase imaging (QPI) has emerged as a valuable method for investigating cells
and tissues. QPI operates on unlabelled specimens and, as such, is complementary to …