Trehalose-deficient Acinetobacter baumannii exhibits reduced virulence by losing capsular polysaccharide and altering membrane integrity
CS Crippen, J Glushka, E Vinogradov… - …, 2021 - academic.oup.com
Acinetobacter baumannii has become a leading cause of bacterial nosocomial infections, in
part, due to its ability to resist desiccation, disinfection and antibiotics. Several factors …
part, due to its ability to resist desiccation, disinfection and antibiotics. Several factors …
Trehalose, a temperature‐ and salt‐induced solute with implications in pathobiology of Acinetobacter baumannii
S Zeidler, J Hubloher, K Schabacker… - Environmental …, 2017 - Wiley Online Library
Acinetobacter baumannii is an opportunistic human pathogen that has become a global
threat to healthcare institutions worldwide. A major factor contributing to success of this …
threat to healthcare institutions worldwide. A major factor contributing to success of this …
Trehalose‐6‐phosphate‐mediated phenotypic change in Acinetobacter baumannii
JJ Hubloher, S Zeidler, P Lamosa… - Environmental …, 2020 - Wiley Online Library
The stress protectant trehalose is synthesized in Acinetobacter baumannii from UPD‐
glucose and glucose‐6‐phosphase via the OtsA/OtsB pathway. Previous studies proved that …
glucose and glucose‐6‐phosphase via the OtsA/OtsB pathway. Previous studies proved that …
[HTML][HTML] Identification of a General O-linked Protein Glycosylation System in Acinetobacter baumannii and Its Role in Virulence and Biofilm Formation
Acinetobacter baumannii is an emerging cause of nosocomial infections. The isolation of
strains resistant to multiple antibiotics is increasing at alarming rates. Although A. baumannii …
strains resistant to multiple antibiotics is increasing at alarming rates. Although A. baumannii …
Trehalose and bacterial virulence
M Vanaporn, RW Titball - Virulence, 2020 - Taylor & Francis
Trehalose is a disaccharide of two D-glucose molecules linked by a glycosidic linkage,
which plays both structural and functional roles in bacteria. Trehalose can be synthesized …
which plays both structural and functional roles in bacteria. Trehalose can be synthesized …
[HTML][HTML] Trehalose and α-glucan mediate distinct abiotic stress responses in Pseudomonas aeruginosa
SD Woodcock, K Syson, RH Little, D Ward… - PLoS …, 2021 - journals.plos.org
An important prelude to bacterial infection is the ability of a pathogen to survive
independently of the host and to withstand environmental stress. The compatible solute …
independently of the host and to withstand environmental stress. The compatible solute …
The trehalose-specific transporter LpqY-SugABC is required for antimicrobial and anti-biofilm activity of trehalose analogues in Mycobacterium smegmatis
JM Wolber, BL Urbanek, LM Meints, BF Piligian… - Carbohydrate …, 2017 - Elsevier
Mycobacteria, including the bacterial pathogen that causes human tuberculosis, possess
distinctive pathways for synthesizing and utilizing the non-mammalian disaccharide …
distinctive pathways for synthesizing and utilizing the non-mammalian disaccharide …
The role of compatible solutes in desiccation resistance of Acinetobacter baumannii
S Zeidler, V Müller - Microbiologyopen, 2019 - Wiley Online Library
Acinetobacter baumannii is a nosocomial pathogen which can persist in the hospital
environment not only due to the acquirement of multiple antibiotic resistances, but also …
environment not only due to the acquirement of multiple antibiotic resistances, but also …
[HTML][HTML] Trehalose metabolism: A sweet spot for Burkholderia pseudomallei virulence
S Schwarz, P Van Dijck - Virulence, 2017 - Taylor & Francis
Trehalose is a sugar composed of 2 aD-glucose molecules linked by an a, a-1, 1-glucoside
bond which is produced by a variety of organisms such as bacteria, archeae, fungi, plants …
bond which is produced by a variety of organisms such as bacteria, archeae, fungi, plants …
[HTML][HTML] Diversity and function of capsular polysaccharide in Acinetobacter baumannii
JK Singh, FG Adams, MH Brown - Frontiers in microbiology, 2019 - frontiersin.org
The Gram-negative opportunistic bacterium Acinetobacter baumannii is a significant cause
of hospital-borne infections worldwide. Alarmingly, the rapid development of antimicrobial …
of hospital-borne infections worldwide. Alarmingly, the rapid development of antimicrobial …
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