Background Chemical liver injury is one of the main causes of acute liver failure and death.
To date, however, treatment strategies for acute liver injury have been limited. Therefore …

Thymol is a natural antibacterial agent found in the essential oil extracted from thyme, which
has been proven to be beneficial in food and medicine. Meanwhile, the NOD-like receptor …

The past decades have witnessed significant progress in understanding the process of
sterile inflammation, which is dependent on a cytosolic complex termed the nucleotide …

Background Lycopene is a naturally occurring carotenoid found in many fruits and
vegetables, which has antioxidant effects. Although lycopene's protective effect has been …

Pure plant extract luteolin has been demonstrated to possess numerous biological effects.
However, the specific effect of luteolin on macrophage polarization and NOD-like receptor …

Acute liver failure (ALF) is a dramatic liver disease characterized by large areas of
inflammation. However, there are no available effective targeted drugs for ALF treatment. In …

Lipopolysaccharide (LPS)-induced liver injury is the main factor in acute liver failure. The
current study aims to investigate the protection of limonin, an antioxidant compound from …

Lycium barbarum has been used as a traditional Chinese medicine to nourish liver, kidneys
and the eyes. However, the underlying mechanisms of its hepatic-protective properties …

Severe hepatotoxicity greatly limits the clinical application of the first-line anti-tuberculosis
drug isoniazid (INH). Quercetin (Que) has multiple pharmacological properties, and is …

Sepsis-related acute liver injury (ALI) is a fatal disease associated with many complications.
Recent studies indicate that malvidin, an active flavonoid, has multiple bioactivities including …