The genetic and environmental factors of primary membranous nephropathy: an overview from China

X Zhang, Z Cui, M Zhao - Kidney Diseases, 2018 - karger.com
Background: Primary membranous nephropathy (pMN) is the most common cause of
nephrotic syndrome in adults. The discovery of the 2 autoantigens, M-type phospholipase …

Analysis of PLA2R1 and HLA-DQA1 sequence variants in Japanese patients with idiopathic and secondary membranous nephropathy

H Kaga, A Komatsuda, A Omokawa, S Okuyama… - Clinical and …, 2018 - Springer
Background Several recent studies in patients with idiopathic membranous nephropathy
(iMN) from Western and Asian counties showed that some single nucleotide polymorphisms …

Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies

P Sekula, Y Li, HC Stanescu, M Wuttke… - Nephrology Dialysis …, 2017 - academic.oup.com
Background: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in
adults. Previous genome-wide association studies (GWAS) of 300 000 genotyped variants …

Recent progress in deciphering the etiopathogenesis of primary membranous nephropathy

A Kronbichler, J Oh, B Meijers… - BioMed research …, 2017 - Wiley Online Library
Primary membranous nephropathy (MN) is the leading cause of nephrotic syndrome in
adults. Discovery of several antibodies has contributed to an increased understanding of …

Advances in pathogenesis of idiopathic membranous nephropathy

Z Xu, L Chen, H Xiang, C Zhang, J Xiong - Kidney Diseases, 2020 - karger.com
Abstract Background: Membranous nephropathy (MN), a major cause of nephrotic
syndrome, has attracted people's attention in recent years for its growing prevalence. It is the …

[HTML][HTML] Gene polymorphism and risk of idiopathic membranous nephropathy

D Liu, J Zhang, Y Shi, Z Liu - Life sciences, 2019 - Elsevier
Membranous nephropathy (MN) is the most common primary glomerular disease (PGD) in
the world. Currently, MN still lacks specific diagnostic markers and effective treatment …

Genetics of membranous nephropathy

S Gupta, A Köttgen, E Hoxha… - Nephrology Dialysis …, 2018 - academic.oup.com
An HLA-DR3 association with membranous nephropathy (MN) was described in 1979 and
additional evidence for a genetic component to MN was suggested in 1984 in reports of …

[HTML][HTML] Genetic susceptibility to idiopathic membranous nephropathy in high-prevalence Area, Taiwan

SY Chen, CH Chen, YC Huang, CJ Chan, DC Chen… - BioMedicine, 2014 - Springer
Idiopathic membranous nephropathy (MN) is one common cause of idiopathic nephrotic
syndrome in adults; 25% of MN patients proceed to end-stage renal disease. In adults …

HLA-DRB1* 15: 01 and HLA-DRB3* 02: 02 in PLA2R-related membranous nephropathy

WB Le, JS Shi, T Zhang, L Liu, HZ Qin… - Journal of the …, 2017 - journals.lww.com
Idiopathic membranous nephropathy (MN) is associated with HLA; however, the HLA allele
involved remains unknown. To identify the HLA risk alleles associated with phospholipase …

[HTML][HTML] Identification of a two-SNP PLA2R1 Haplotype and HLA-DRB1 Alleles as Primary Risk Associations in Idiopathic Membranous Nephropathy

KZ Latt, K Honda, M Thiri, Y Hitomi, Y Omae, H Sawai… - Scientific reports, 2018 - nature.com
The associations of single nucleotide polymorphisms (SNPs) in PLA2R1 and HLA-DQA1, as
well as HLA-DRB1* 15: 01-DQB1* 06: 02 haplotype with idiopathic membranous …