[HTML][HTML] A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19

OJ McElvaney, BD Hobbs, D Qiao, OF McElvaney… - …, 2020 - thelancet.com
Background Prognostic tools are required to guide clinical decision-making in COVID-19.
Methods We studied the relationship between the ratio of interleukin (IL)-6 to IL-10 and …

Prompt predicting of early clinical deterioration of moderate-to-severe COVID-19 patients: usefulness of a combined score using IL-6 in a preliminary study

A Vultaggio, E Vivarelli, G Virgili, E Lucenteforte… - The Journal of Allergy …, 2020 - Elsevier
Background The early identification of patients at risk of clinical deterioration is of interest
considering the timeline of COVID-19 after the onset of symptoms. Objective The aim of our …

[HTML][HTML] Interleukine-6 in critically ill COVID-19 patients: A retrospective analysis

J Gorham, A Moreau, F Corazza, L Peluso… - PLoS …, 2020 - journals.plos.org
Introduction Coronavirus disease 2019 (COVID-19) appeared in China in December 2019
and has spread around the world. High Interleukin-6 (IL-6) levels in COVID-19 patients …

Cytokine prediction of mortality in COVID19 patients

M Mandel, G Harari, M Gurevich, A Achiron - Cytokine, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID19) is a life-threatening infection with uncertain
progression and outcome. Assessing the severity of the disease for worsening patients is of …

[HTML][HTML] A score combining early detection of cytokines accurately predicts COVID-19 severity and intensive care unit transfer

C Nagant, F Ponthieux, J Smet, N Dauby… - International Journal of …, 2020 - Elsevier
Objectives We aimed to explore cytokine profile in patients as it relates to Coronavirus
Disease 2019 (COVID-19) severity, and to establish a predictive cytokine score to …

[PDF][PDF] IL-6 and IL-10 as predictors of disease severity in COVID-19 patients: results from meta-analysis and regression

SK Dhar, K Vishnupriyan, S Damodar, S Gujar, M Das - Heliyon, 2021 - cell.com
Abstract Aims SARS-CoV-2, an infectious agent behind the ongoing COVID-19 pandemic,
induces high levels of cytokines such as IL-1, IL-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ etc in …

Prognostic bioindicators in severe COVID-19 patients

L Bergantini, E Bargagli, M d'Alessandro, RM Refini… - Cytokine, 2021 - Elsevier
Background Severe acute respiratory syndrome caused by novel coronavirus 2 (SARS-CoV-
2) emerged in Wuhan (China) in December 2019. Here we evaluated a panel of biomarkers …

[HTML][HTML] Dynamic interleukin-6 level changes as a prognostic indicator in patients with COVID-19

Z Liu, J Li, D Chen, R Gao, W Zeng, S Chen… - Frontiers in …, 2020 - frontiersin.org
Background Interleukin-6 (IL-6), a proinflammatory cytokine, has been reported to be
associated with disease severity and mortality in patients with coronavirus disease 2019 …

[HTML][HTML] IL-6 and CD8+ T cell counts combined are an early predictor of in-hospital mortality of patients with COVID-19

M Luo, J Liu, W Jiang, S Yue, H Liu, S Wei - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND Fatal cases of COVID-19 are increasing globally. We retrospectively
investigated the potential of immunologic parameters as early predictors of COVID-19 …

[HTML][HTML] Inflammatory phenotyping predicts clinical outcome in COVID-19

H Burke, A Freeman, DC Cellura, BL Stuart… - Respiratory …, 2020 - Springer
Background The COVID-19 pandemic has led to more than 760,000 deaths worldwide
(correct as of 16th August 2020). Studies suggest a hyperinflammatory response is a major …