Melanoma is the most lethal skin cancer that originates from the malignant transformation of
melanocytes. Although melanoma has long been regarded as a cancerous malignancy with …

This review aims to summarize the current knowledge of molecular pathways and their
clinical relevance in melanoma. Metastatic melanoma was a grim diagnosis, but in recent …

Melanoma, the deadliest form of skin cancer, is an aggressive disease that is rising in
incidence. Although melanoma is a historically treatment-resistant malignancy, in recent …

Metastatic melanoma remained for decades without any effective treatment and was thus
considered as a paradigm of cancer resistance. Recent progress with understanding of the …

Melanoma is a relentless type of skin cancer which involves myriad signaling pathways
which regulate many cellular processes. This makes melanoma difficult to treat, especially …

The incidence of melanoma is increasing at one of the highest rates of any form of cancer in
the United States, with the current lifetime risk being one in 68. At present, there are limited …

In less than 10 years, melanoma treatment has been revolutionized with the approval of
tyrosine kinase inhibitors and immune checkpoint inhibitors, which have been shown to …

Melanoma is the most aggressive and dangerous form of skin cancer that develops from
transformed melanocytes. It is crucial to identify melanoma at its early stages, in situ, as it is …

Malignant melanoma presents a substantial clinical challenge. Current diagnostic methods
are limited in their ability to diagnose early disease and accurately predict individual risk of …

Cutaneous melanoma is the most common skin cancer with an incidence that has been
rapidly increasing in the past decades. Melanomas are among the most immunogenic …