Current clinical landscape and global potential of bacteriophage therapy
NM Hitchcock, D Devequi Gomes Nunes, J Shiach… - Viruses, 2023 - mdpi.com
In response to the global spread of antimicrobial resistance, there is an increased demand
for novel and innovative antimicrobials. Bacteriophages have been known for their potential …
for novel and innovative antimicrobials. Bacteriophages have been known for their potential …
Bacteriophage therapy: clinical trials and regulatory hurdles
LL Furfaro, MS Payne, BJ Chang - Frontiers in cellular and infection …, 2018 - frontiersin.org
Increasing reports of antimicrobial resistance and limited new antibiotic discoveries and
development have fuelled innovation in other research fields and led to a revitalization of …
development have fuelled innovation in other research fields and led to a revitalization of …
Bacteriophage therapy: Developments and directions
MP Nikolich, AA Filippov - Antibiotics, 2020 - mdpi.com
In an era of proliferating multidrug resistant bacterial infections that are exhausting the
capacity of existing chemical antibiotics and in which the development of new antibiotics is …
capacity of existing chemical antibiotics and in which the development of new antibiotics is …
Phage therapy in the twenty-first century: facing the decline of the antibiotic era; is it finally time for the age of the phage?
S Hesse, S Adhya - Annual review of microbiology, 2019 - annualreviews.org
Burgeoning problems of antimicrobial resistance dictate that new solutions be developed to
combat old foes. Use of lytic bacteriophages (phages) for the treatment of drug-resistant …
combat old foes. Use of lytic bacteriophages (phages) for the treatment of drug-resistant …
Re-establishing a place for phage therapy in western medicine
Use of bacterial viruses as antibacterial agents has a history nearly as long as the now 100-
year study of bacteriophages. Therapeutic phages are especially useful in the absence of …
year study of bacteriophages. Therapeutic phages are especially useful in the absence of …
A phage therapy guide for clinicians and basic scientists: background and highlighting applications for developing countries
A Khalid, RCY Lin, JR Iredell - Frontiers in Microbiology, 2021 - frontiersin.org
Approximately 10% of global health research is devoted to 90% of global disease burden
(the so-called “10/90 Gap”) and it often neglects those diseases most prevalent in low …
(the so-called “10/90 Gap”) and it often neglects those diseases most prevalent in low …
Phage therapy in the postantibiotic era
FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …
number of infections are becoming harder or almost impossible to treat, carrying high …
Bacteriophages as alternatives to antibiotics in clinical care
D Romero-Calle, R Guimarães Benevides… - Antibiotics, 2019 - mdpi.com
Antimicrobial resistance is increasing despite new treatments being employed. With a
decrease in the discovery rate of novel antibiotics, this threatens to take humankind back to …
decrease in the discovery rate of novel antibiotics, this threatens to take humankind back to …
Bacteriophage Therapy for Difficult-to-Treat Infections: The Implementation of a Multidisciplinary Phage Task Force (The PHAGEFORCE Study Protocol)
In times where only a few novel antibiotics are to be expected, antimicrobial resistance
remains an expanding global health threat. In case of chronic infections caused by therapy …
remains an expanding global health threat. In case of chronic infections caused by therapy …
Phage therapy for antibiotic-resistant bacterial infections
GF Hatfull, RM Dedrick… - Annual Review of …, 2022 - annualreviews.org
Antibiotic resistance in bacterial pathogens presents a substantial threat to the control of
infectious diseases. Development of new classes of antibiotics has slowed in recent years …
infectious diseases. Development of new classes of antibiotics has slowed in recent years …
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