Three-dimensional porous scaffolds are substitutes for traditional bone grafts in bone tissue
engineering (BTE) applications to restore and treat bone injuries and defects. The use of …

The use of biocompatible and biodegradable porous scaffolds produced via additive
manufacturing is one of the most common approaches in tissue engineering. The geometric …

The effectiveness of fabricated bone scaffolds to mimic exact bone tissue can be evaluated
based on the mechanical strength and fluid dynamic behaviour. The fluid dynamic …

Through the recent years, tissue engineering has been proven as a solid substitute of
autografts in the stimulation of bone tissue regeneration, through the development of three …

Bone injuries or defects that require invasive surgical treatment are a serious clinical issue,
particularly when it comes to treatment success and effectiveness. Accordingly, bone tissue …

Abstract Three-dimensional (3D) porous tissue scaffolds combined with bioactive molecules
and cells offer key advantages for bone repair mechanisms. A functional bone tissue …

Purpose This paper aims to develop a computational approach to analyze the mechanical
behavior, perfusion bioreactor test and degradation of the designed scaffolds. Five types of …

The most common solution for the regeneration or replacement of damaged bones is the
implantation of prostheses comprising ceramic or metallic materials. However, these …

Bioreactor system has been used in bone tissue engineering in order to simulate dynamic
nature of bone tissue environments. Perfusion bioreactors have been reported as the most …

Bone tissue engineering strategies use flow through perfusion bioreactors to apply
mechanical stimuli to cells seeded on porous scaffolds. Cells grow on the scaffold surface …