RNA-binding proteins and their role in kidney disease

L Seufert, T Benzing, M Ignarski… - Nature Reviews …, 2022 - nature.com
RNA-binding proteins (RBPs) are of fundamental importance for post-transcriptional gene
regulation and protein synthesis. They are required for pre-mRNA processing and for RNA …

Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease

S Gerstberger, M Hafner, M Ascano… - Systems biology of RNA …, 2014 - Springer
RNA-binding proteins (RBPs) are effectors and regulators of posttranscriptional gene
regulation (PTGR). RBPs regulate stability, maturation, and turnover of all RNAs, often …

RNA-binding proteins in human genetic disease

F Gebauer, T Schwarzl, J Valcárcel… - Nature Reviews …, 2021 - nature.com
RNA-binding proteins (RBPs) are critical effectors of gene expression, and as such their
malfunction underlies the origin of many diseases. RBPs can recognize hundreds of …

RNA-binding proteins in human genetic disease

KE Lukong, K Chang, EW Khandjian, S Richard - Trends in Genetics, 2008 - cell.com
RNA-binding proteins (RBPs) are key components in RNA metabolism, regulating the
temporal, spatial and functional dynamics of RNAs. Altering the expression of RBPs has …

RNA-binding proteins hold key roles in function, dysfunction, and disease

S Kelaini, C Chan, VA Cornelius, A Margariti - Biology, 2021 - mdpi.com
Simple Summary Chronic hyperglycemia manifests in a variety of different micro-and
macrovascular disorders such as diabetes mellitus and cardiovascular disease and has …

[HTML][HTML] RNA-binding proteins and post-transcriptional gene regulation

T Glisovic, JL Bachorik, J Yong, G Dreyfuss - FEBS letters, 2008 - Elsevier
RNAs in cells are associated with RNA-binding proteins (RBPs) to form ribonucleoprotein
(RNP) complexes. The RBPs influence the structure and interactions of the RNAs and play …

Cancer the 'RBP'eutics–RNA-binding proteins as therapeutic targets for cancer

S Mohibi, X Chen, J Zhang - Pharmacology & therapeutics, 2019 - Elsevier
RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

The expanding universe of ribonucleoproteins: of novel RNA-binding proteins and unconventional interactions

BM Beckmann, A Castello, J Medenbach - Pflügers Archiv-European …, 2016 - Springer
Post-transcriptional regulation of gene expression plays a critical role in almost all cellular
processes. Regulation occurs mostly by RNA-binding proteins (RBPs) that recognise RNA …

Emerging roles of disordered sequences in RNA-binding proteins

S Calabretta, S Richard - Trends in biochemical sciences, 2015 - cell.com
RNA-binding proteins (RBPs) maintain RNA metabolism homeostasis in the cell by
regulating temporal, spatial, and functional dynamics of RNAs. RBPs achieve RNA binding …

The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs

BM Beckmann, R Horos, B Fischer, A Castello… - Nature …, 2015 - nature.com
RNA-binding proteins (RBPs) exert a broad range of biological functions. To explore the
scope of RBPs across eukaryotic evolution, we determined the in vivo RBP repertoire of the …